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Coconut Oil Promotes Greater Satiety and Reduces Blood Cholesterol, But Induces Obesity, Anxiety and Impaired Bone Formation in Adult Wistar Rats

DOI: 10.18805/ag.D-302    | Article Id: D-302 | Page : 548-553
Citation :- Coconut Oil Promotes Greater Satiety and Reduces Blood Cholesterol, But Induces Obesity, Anxiety and Impaired Bone Formation in Adult Wistar Rats.Agricultural Science Digest.2021.(41):548-553
Ítalo Gomes Reis, Arthur Rocha-Gomes, Alexandre Alves da Silva, Mayara Rodrigues Lessa, Nísia Andrade Villela Dessimoni Pinto, Tania Regina Riul italogomesreis@gmail.com
Address : Universidade Federal dos Vales do Jequitinhonha e Mucuri, MGT 367 Highway (Km 583), Campus JK, nº 5000, Alto da Jacuba, Diamantina-MG, Brazil. 
Submitted Date : 12-08-2020
Accepted Date : 5-11-2020

Abstract

Background: The aim of this study was to evaluate the nutritional effects of supplementation with virgin coconut oil (VCO) in Wistar rats over a sub-chronic period (6 weeks).
Methods: Twelve Wistar rats were used and randomly assigned to receive (n = 6): control - lab chow; coconut oil (CO) - lab chow with added virgin coconut oil (20%). Food and caloric intake, weight gain, food efficiency, body mass index, femur and tibia length, bone mineral composition and blood biochemistry were evaluated.
Result: The CO group showed an energy intake closed to control group. Also, the supplementation with VCO generated a decrease in total blood cholesterol as compared to the control group. However, the CO group showed accumulation of fat mass, shorter femur length and anxiogenesis in relation to the control group. These results indicate few beneficial effects from the sub-chronic use of VCO and indicate that its consumption in large quantities for long periods should be questioned.

Keywords

Cholesterol Medium-chain triglycerides Obesity Satiety Saturated fatty acids Virgin coconut oil Wistar

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