Agricultural Reviews

  • Chief EditorPradeep K. Sharma

  • Print ISSN 0253-1496

  • Online ISSN 0976-0741

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Agricultural Reviews, volume 35 issue 2 (june 2014) : 148-152

GENOMIC IMPRINTING IN MAMMALS - A REVIEW

Parul Gupta*, Dibyendu Chakraborty1, Raman Taggar, Dhirendra Kumar, Rajan Sharma, Vishav P. Singh
1Division of Animal Genetics and Breeding SKUAST-J, R.S. Pura, Jammu-181 102, India
Cite article:- Gupta* Parul, Chakraborty1 Dibyendu, Taggar Raman, Kumar Dhirendra, Sharma Rajan, Singh P. Vishav (2024). GENOMIC IMPRINTING IN MAMMALS - A REVIEW. Agricultural Reviews. 35(2): 148-152. doi: 10.5958/0976-0741.2014.00093.2.
Genomic imprinting refers to an epigenetic mark that distinguishes parental alleles and results in a monoallelic, parental-specific expression pattern in mammals. The alleles of imprinted genes are marked epigenetically as discrete elements termed imprinting control regions with their parental origin in gametes through the use of DNA methylation, at the very least. Imprinted genes are normally involved in foetal growth and behavioural development. Consequently, aberrant imprinting disturbs development and is the cause of numerous well-known imprinting disorders, including Beckwith-Wiedemann syndrome, Prader-Willi syndrome, Cancer and Angelman syndrome.
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