Tackling the Covid-19 Pandemic in Animal Facilities: ACTREC Perspectives

DOI: 10.18805/ag.R-2089    | Article Id: R-2089 | Page : 203-208
Citation :- Tackling the Covid-19 Pandemic in Animal Facilities: ACTREC Perspectives.Agricultural Reviews.2021.(42):203-208
R.A. Thorat, A.D. Ingle aingle@actrec.gov.in
Address : Laboratory Animal Facility, Advanced Centre for Treatment, Research and Education in Cancer (ACTREC), Tata Memorial Centre, Kharghar, Navi Mumbai, 410 210, MS, India.
Submitted Date : 26-08-2020
Accepted Date : 29-10-2020


The Novel Coronavirus outbreak gave learning lesson to the entire world especially about how to fight with the invisible enemy. The scientific community is engaged in exploring the pathogenesis of this Novel disease and inventing the antivirals. At the same time, laboratory animal facility key personnel are busy in carrying out facility operations without compromising the laboratory animal welfare and on-going animal research. In general, every laboratory animal facility establishes the disaster management plan considering the possibility of fire, earthquake, cyclones or flood. Advanced Centre for Treatment, Research and Education in Cancer (ACTREC) Animal Facility also has well documented disaster plan in place. However, incorporation of preparedness plan against disaster due to pandemic was never thought of. However, with our extensive experience, great team efforts and timely decisions, we could continue facility operations without compromising animal welfare, on-going animal research and health of animal care personnel. It is the need of hour to make a preparedness plan in advance to respond to any kind of such pandemics in the future. We wish to share our experience gained during SARS-CoV-2 pandemics. This data is concerned about us but may be helpful to other animal facilities in India and/ or across the globe.


Animal facilities Pandemic Tackling Preparedness


  1. AAALAC International FAQs for COVID-19 April 2020. Accessed at https://www.aaalac.org/pub/?id=2636C0F1-BDF6-C7F4-505D-5633E981D290.
  2. Bardelli, A. (2020). Coronavirus lockdown: What I learnt when I shut my cancer lab in 48 hours. Nature. doi: 10.1038/d41586-020-00826-7. 
  3. CPCSEA notification http://cpcsea.nic.in/WriteReadData/LnPdf/    IAECmeetingsduringlockdown.pdf .
  4. Cucinotta, D. and Vanelli, M. (2020). WHO Declares Covid-19 a Pandemic, Acta Biomed. 91(1): 157- 60. 
  5. Glass, R.J., Glass, L.M., Beyeler, W.E., Min H.J. (2006). Targeted social distancing design for pandemic influenza. Emerging Infectious Diseases. 12(11): 1671-1681.
  6. ICMR-NIRRH Guidelines for pregnant women in Covid-19 pandemic. Available at https://www.icmr.gov.in/pdf/covid/techdoc/Guidance_for_Management_of_Pregnant_Women_in_ COVID19_Pandemic_12042020.pdf.
  7. Li Q., Guan, X., Wu, P., Wang, X., Zhou, L, Tong, Y., et al. (2020). Early transmission dynamics in Wuhan, China, of novel coronavirus-infected pneumonia. The New England Journal of Medicine. 382(13): 1199-1207.
  8. Mullen, L., Potter, C., Gostin, L.O., Cicero, A., Nuzzo, J.B. (2020). An Analysis of International Health Regulations Emergency Committees and Public Health Emergency of International Concern Designations, BMJ Global Health. 5: e002502 doi:10.1136/bmjgh-2020-002502
  9. Nowogrodzki, A. (2020). Cull, release or bring them home: Coronavirus crisis forces hard decisions for labs with animals. Nature. 580: 19. 
  10. Thorat, R. and Ingle, A. (2012). An attempt of cryopreservation of mouse embryos at the ACTREC Laboratory Animal Facility in India. Experimental Animals. 61(2): 139-145.
  11. Thorat, R., Ahire, S. and Ingle, A. (2013). Re-establishment of a breeding colony of immunocompromised mice through revival of cryopreserved embryos. Lab Animmal. 4: 131-134.
  12. Walawalkar, S., Khattry, N., Sapra, B.K., Khan, A., Joshi, M., Mohan, L., Srivastava, S.P., Naresh, C., Badwe, R., Gupta, S. (2020) High Filtration Efficiency Face Masks made from Sterilization Wraps. medRxiv doi: https://doi.org/10.1101/2020.05.17.20104638. 
  13. World Health Organization. Coronavirus disease (2019). (COVID-19): Situation Report – 38. 27 February 2020. Accessed at https://www.who.int/docs/default-source/coronaviruse/situation-reports/20200227-sitrep-38-covid-19.pdf?sfvrsn =2db7a09b_4.
  14. Zhu, N., Zhang, D., Wang, W., Li, X., Yang, B., Song, J., Zhao, X., Huang, B., Shi W., Lu, R., Niu, P., Zhan, F. (2019). A novel coronavirus from patients with pneumonia in China. The New England Journal of Medicine. 382(8): 727-733 (2020).

Global Footprints