Agricultural Reviews

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Agricultural Reviews, volume 38 issue 4 (december 2017) : 297-303

Potentiating immunity of dairy animals during transition period through herbs - A review

Subhash Chandra, M.L. Kamboj, Anjali Kumari, Amit Kumar, Haneef A. Rather
1ICAR-National Dairy Research Institute, Karnal-132 001, Haryana, India.
Cite article:- Chandra Subhash, Kamboj M.L., Kumari Anjali, Kumar Amit, Rather A. Haneef (2017). Potentiating immunity of dairy animals during transition period throughherbs - A review. Agricultural Reviews. 38(4): 297-303. doi: 10.18805/ag.R-1654.
India has a rich diversity of medicinal plants and traditional knowledge on herbal medicine to treat the animals has both curative and preventive roles. Immunity of the animals affects the is production potential. Strengthening of non-specific immunity of the parturient animals can be used as an alternative approach to overcome the incidence of diseases in the peri and postpartum period where in these animals are more prone. One of the promising technologies is the use of immunomodulators to boost the immunity of animals during the transition period. Immunomodulators can be of natural or synthetic origin, which helps in boosting up the immunity for overcoming stress-related ailments, inhibition of reactive oxygen species generation and scavenging of free radicals to ensure the general wellbeing of animals. In the recent years, several different approaches have been examined to investigate the effect of various herb extracts and minerals as immunopotentiator separately. In literature many plants have been listed having immunomodulatory effect and some of them have been proved to have active principles with immunomodulatory, antioxidant, analgesic, antipyretic and antimicrobial properties. The present compilation deals with some of such medicinal plants like Anethum graveolens (Sowa), Elettaria cardamomum (Bari elaichi/Cardamom), Foeniculum vulgare (Saunf), Trachyspermum ammi (Ajwain), Zingiber officinale (Sundh) and Trigonella foenun- graceum etc.
  1. Abraham P. (1965). The cardamom in India. [Kachroo P. (ed.)] Farm. Bull. (New Series). ICAR, New Delhi 37: 1-46. 
  2. Agaoglu, S., Dostbil, N. and Alemdar, S. (2005). Antimicrobial effect of seed extract of cardamom (Elettarýa cardamom Maton). YYÜ Vet Fak Derg, 16 (2): 99, 101, 477-480. 
  3. Agarwal, R., Gupta, S.K., Agarwal, S.S., Srivastava, S. and Saxena, R. (2008). Oculohypotensive effects of Foeniculum vulgare in experimental models of glaucoma. Indian J. Physiol. Pharmacol, 52: 77–83.
  4. Ahmadiani, A., Javan, M., Semnanian, S., Barat, E. and Kamalinejad, M. (2001). antiinflammatory and antipyretic effects of Trigonella foenum- graecum leaves extract in the rat. J. Ethnopharmacol., 75(2): 283-286.
  5. Al Meshal, I. A., Parmar, N. S., Tariq, M. and Ageel, A. M. (1985). Gastric anti-ulcer activity in rats of Trigonella foenum-graecum (Hu-Lu-Pa) Fitoterapia, 56: 232-235.
  6. Al-Habori, M. and Raman, A. (1988). Antidiabetic and hypocholesterolemic effects of fenugreek. Phyto. Res., 12: 233–242. 
  7. Al-Yahya, M. A., Rafatullah, S., Mossa, J. S., Ageel, A. M., Parmar, N. S. and Tariq, M. (1989). Gastroprotective activity of ginger Zingiber officinale, in albino rats. The American journal of Chinese Medicine, 17:51-56. 
  8. Al-Zuhair, H., El-Sayeh, B., Ameen, H. A. and Al-Shoora, H. (1996). Pharmacological studies of cardamom oil in Animals Pharmacol. Res., 34 (1): 79-82.
  9. Amir, M., Khan, A., Mujeeb, M., Ahmad, A., Usmani, S. and Akhtar, M. (2011). Phytochemical analysis and in vitro antioxidant activity of Zingiber officinale. Free Radicals and Antioxidants, 1(4), 75-81. 
  10. Ashish, R., Hossain, M. B., Patras, A., Tuohy, M. and Brunton, N. (2013). Effect of boiling and roasting on the polyacetylene and polyphenol content of fennel (Foeniculum vulgare) bulb. Food Research International, 50 (2), 513-518.
  11. Bilal, B.H., Rizwarul, H., Suhel, P., Suwarna, P., Iqbal, S. and Raisuddin, S. (2003). Immunomodulatory effects of fenugreek extract in mice. Int. Immunopharmacol, 3: 257–265.
  12. Calflora taxon report, (2014). University of California, Foeniculum vulgare Miller, Biscuit root, fennel, sweet fenne.
  13. Calsamiglia, S. , Busquet, M. , Cardozo, P. W. , Castillejos, L., Ferret, A. and Fandiño, I. (2007). The Use of Essential Oils in Ruminants as Modifiers of Rumen Microbial Fermentation. Penn State Dairy Cattle Nutrition Workshop.
  14. Camejo-Rodrigues, J. S., Ascensão, L., Bone, T. M. A. and Vallès, J. (2003). An ethnobotanical study of medicinal and aromatic plants in the Natural Park of Serra de S. Mamede (Portugal). J. Ethnopharmacol., 89: 199"209.
  15. Cantore, P.L., N.S. Iacobellis, A.D. Marco, F. Capasso and F. Senatore. (2004). Antibacterial Activity of Coriandrum sativum L. and Foeniculum vulgare Miller Var. vulgare (Miller) Essential Oils. J. Agric. Food Chem., 52(26): 7862-7866s.
  16. Chandra, S., Oberoi, P. S., Singh, P. K., Barjibhe, S., Kumar, A., Bhakat, M, Kumar, N and Dang, A. K. (2016). Effect of Poly-herbal mixture and butyric acid feeding on immune parameters of postpartum Murrah buffaloes. Indian Journal of Animal Research, (OF). 
  17. Chang, C., Griffith, G., and Maino, G. (2011). The feasibility of fresh ginger exports from Papua New Guinea to New Zealand. Australasian Agribusiness Review, 19, 75-97.
  18. Chauhan. B., Kumar, G. and Ali, M. (2012) A Review on phytochemical constituents and activities of Trachyspermum ammi (L.) sprague fruits. AJPTR. 2(4):329–40.
  19. Choi, E. M. and Hwang, J. K. (2004). Anti-inflammatory, analgesic and antioxidant activities of the fruit of Foeniculum vulgare. Fitoterapia, 75: 557-565. 
  20. Choi, W., Jiang, M. and Chu, J. (2013). Antiparasitic effects of Zingiber officinale (Ginger) extract against Toxoplasma gondii. Journal of Applied Biomedicine, 11(1), 15-26. 
  21. Choudhury, S., Ahmed, R., Kanjilal, P. B. and Leclercq, P. A. (1998). Composition of the seed oil of Trachyspermum ammi (L.) Sprague from Northeast India. J Essent Oil Res: JEOR. 10(5):588–90.
  22. Dadalioglu, I. and Evrendilek, G. A. (2004). Chemical compositions and antibacterial effects of essential oils of Turkish oregano (Origanum minutiflorum), bay laurel (Laurus nobilis), Spanish lavender (Lavandula stoechas L.), and fennel (Foeniculum vulgare) on common food borne pathogens. J. Agri. and Food Chem., 52: 8255-8260.
  23. Defrain, J. M., Hippen, A. R., Kalscheur, K. F. and Patton, R. S. (2005). Effect of Feeding ropionate and Calcium Salts of Long-Chain Fatty Acids on Transition Dairy Cow Performance. J. Dai. Sci., 88:983-993.
  24. Denyer, C. V., Jackson, P., Loakes, D. M., Ellis, M. R. and Young, D. A. (1994). Isolation of antirhinoviral sesquiterpenes from ginger (Zingiber officinale). Journal of Natural Products, 57(5), 658-662.
  25. Dodds, E. C., Goldberg, L., Lawson, W. and Robinson, R. (1938). Oestrogenic activity of certain synthetic compounds. Nature, 141(3562), 247-8.1938).
  26. Elgayyar, M., Draughon, F.A. and Golden, D.A. (2001). Antimicrobial activity of essential oils from plants against selected pathogenic and saprophytic microorganisms. J Food Prot., 64(7):1019-1024. 11456186.
  27. El-Soud, N. A., El-Laithy, N., El-Saeed, G., Wahby, M. S., Khalil, M. and Morsy, F. (2011). Antidiabetic activities of Foeniculum vulgare Mill. Essential oil in streptozotocin induced diabetic rats. Macedonian J. Med. Sci., 173: 1857-5773.
  28. Erdogan Orhan, I., and Tareq Hassan Khan, M. (2014). Flavonoid derivatives as potent tyrosinase inhibitors–A survey of recent findings between 2008-2013. Current topics in Medicinal Chemistry, 14(12), 1486-1493. 
  29. Faudale M, Viladomat F, Bastida J, Poli F, Codina C (2008). Antioxidant activity and phenolic composition of wild, edible, and medicinal fennel from different Mediterranean countries. J. Agric. Food Chem. 56: 1912-1920.
  30. Ficker, C. E., Arnason, J. T., Vindas, P. S., Alvarez, L. P., Akpagana, K., Gbeassor, M., ... and Smith, M. L. (2003). Inhibition of human pathogenic fungi by ethnobotanically selected plant extracts. Mycoses, 46(1 2), 29-37.
  31. Fox, I. J., Chowdhury, J. R., Kaufman, S. S., Goertzen, T. C., Chowdhury, N. R., that. (1998). Treatment of the Crigler–Najjar syndrome type I with hepatocyte transplantation. New England Journal of Medicine, 338(20), 1422-1427. 
  32. Goff, J.P. (2000). Matitis and retained placenta relationship to bovine immunology and nutrition. USDA, Metabolic Diseases and Immunology Research Unit, Ames, IA5001-0-070, USA. 
  33. Goff, J.P. (2006). Major advances in our understanding of nutritional influences on bovine health. J. Dairy Sci. 89: 1292-1301.
  34. Govindarajan V. S. (1982). Ginger Fchemistry, technology and quality evaluation: part 2. CRC Crit Rev Sci Nutr; 17: 189–258. 
  35. Grummer, R. R. (1995). Impact of changes in organic nutrient metabolism on feeding the transition dairy cow. Indian J. Dai. Sci., 73(9), 2820-2833.
  36. Grzanna, R., Lindmark, L., and Frondoza, C. G. (2005). Ginger—an herbal medicinal product with broad anti-inflammatory actions. Journal of medicinal food, 8 (2), 125-132.
  37. Han, M.-K., Kim, S.I. and Ahn, Y.-J. (2006). Insecticidal and antifeedant activities of medicinal plant extracts against Attagenus unicolor japonicas (Coleoptera: Dermestidae). J. Stored Prod. Res., 42: 15–22.
  38. Hare, H. A., Caspari, C. and Rusby, H. H. (1916). The National Standard Dispensatory, Lea and Febiger, Philadelphia, pp., 63 and 1129.
  39. He, J. Z., Zhang, M. Z., and Wang, L. (2010). Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi= Chinese journal of integrated traditional and Western medicine. Zhongguo Zhong xi yi jie he xue hui, Zhongguo Zhong yi yan jiu yuan zhu ban, 30(8), 797-801.
  40. Heamalatha, S., Swarnalatha, S., Divya, M., Gandhi Lakshmi, R., Ganga Devi, A. and Gomathi, E. (2011). Pharmacognostical, pharmacological, investigation on Anethum graveolens Linn: A review. Res. J. Pharmace. Biol. and Chem. Sci., 2: 564-574. 
  41. Hosseinzadeh, H., Karimi, G. R. and Ameri, M. (2010). BMC pharmacology Volume: 2 ISSN: 1471-2210.
  42. Ishikawa, T., Kudo, M., and Kitajima, J. (2002). Water-soluble constituents of dill. Chemical and pharmaceutical bulletin, 50 (4), 501-507.
  43. Jagetia, G. C., Baliga, M. S., Venkatesh, P., and Ulloor, J. N. (2003). Influence of ginger rhizome (Zingiber officinale) on survival, glutathione and lipid peroxidation in mice after whole-body exposure to gamma radiation. Radiation Research, 160 (5), 584-592.
  44. Jana, S., and Shekhawat, G. S. (2010). In vitro Extracts of Indian Medicinal Herb: Anethum grave-olefins.
  45. Jayaweera, D.M.A. (1981). Medicinal Plant: Part III. Peradeniya, Royal Botanic Garden, Sri Lanka: p. 255. 
  46. Jiang, H., Xie, Z., Koo, H. J., McLaughlin, S. P., Timmermann, B. N. and Gang, D. R. (2006). Metabolic profiling and phylogenetic analysis of medicinal Zingiber species: Tools for authentication of ginger (Zingiber officinale). Phytochemistry, 67 (15), 1673-1685. 
  47. Kaur, G. J., and Arora, D. S. (2010). Bioactive potential of Anethum graveolens, Foeniculum vulgare and Trachyspermum ammi belonging to the family Umbelliferae-Current status. Journal of Medicinal Plants Research, 4 (2), 087-094.
  48. Kaushik, P., Goyal, P., Chauhan, A. and Chauhan, G. (2010). In vitro evaluation of antibacterial potential of dry fruit extracts of Elettaria cardamomum Maton (Chhoti Elaichi). Iranian Journal of Pharmaceutical Research, 287-292. 
  49. Kaviarasan, S., Naik, G.H., Gangabhagirathi, R., Anuradha, C.V. and Priyadarsini, K.I. (2007). In vitro studies on antiradical and antioxidant activities of fenugreek (Trigonella foenum graecum) seeds. Food Chem., 103: 31–37.
  50. Kehrli, M. E., Neill, J. D., Burvenich, C., Goff, J. P., Lippolis, J. D., Reinhardt, T. A. and Nonnecke, B. J. (2006). Energy and protein effects on the immune system. Ruminant physiology. Digestion, metabolism and impact of nutrition on gene expression, immunology and stress, 455-471.
  51. Krishnamoorthy, V. (1999). Madalageri MB. Bishop weeds (Trachyspermum ammi): An essential crop for north Karnataka. Journal of Medicinal and Aromatic Plant Sciences, 21 (4), 996-998.
  52. Lee, H. S. (2004). Acaricidal activity of constituents identified in Foeniculum vulgare fruit oil against Dermatophagoides spp.(Acari: Pyroglyphidae). Journal of agricultural and food chemistry, 52 (10), 2887-2889.
  53. Madar, Z. and Arad, J. (1989). Effect of extracted fenugreek on postprandial glucose levels in human diabetic subjects. Nutr. Res., 9: 691–692.
  54. Madar, Z., Abel, R., Samish, S. and Arad, J. (1988). Glucose- lowering effect of fenugreek in non-insulin dependent diabetics. European J. Clin. Nutr. 42: 51–54.
  55. Mahady GB, Pendland SL and Stoia A, Hamill FA, Fabricant D, Dietz BM, Chadwick LR (2005) In vitro susceptibility of Helicobacter pylori to botanical extracts used traditionally for the treatment of gastro- Kaur intestinal disorders. Phytother. Res. 19: 988-991.
  56. Majdalawieh, A. F., and Carr, R. I. (2010). In vitro investigation of the potential immunomodulatory and anti-cancer activities of black pepper (Piper nigrum) and cardamom (Elettaria cardamomum). Journal of Medicinal Food, 13(2), 371-381. 
  57. Manzoor, M., R. Jabeen, S. Irfan, F. Ayub and S. Bibi. (2012). An Ethno botanical Study for the Treatment of Cancer and Malaria Used by the People of Quetta City. Int. J. Basic App. Chem. Sci., 1 (2): 137-149.
  58. Minija J, Thoppil JE (2002) Essential oil composition of Trachyspermum ammi (L.) Sprague from south India. Indian J Pharm Sci 64(3):250–251. 
  59. Moazeni, M., Saharkhiz, M. J. and Hosseini, A. A. (2012). In vitro lethal effect of ajowan (Trachyspermum ammi L.) essential oil on hydatid cyst protoscoleces. Veterinary parasitology, 187(1), 203-208.
  60. Mohsenzadeh M (2007). Evaluation of antibacterial activity of selected Iranian essential oils against Staphylococcus aureus and Escherichia coli in nutrient broth medium. Pak. J. Biol. Sci. 10:3693-3697.
  61. Nair S, Nagar R. and Gupta, R. (1998). Antioxidant phenolics and flavonoids in common Indian foods. J. Assoc Physicians India; 46(8):708-710. 
  62. Natrajan, B., Muralidharan, A., Satish, R. and Dhananjayan, R. (2007). Neuropharmacologicial activity of Trigonella foenum-graecum Linn. Seeds. J. Nat. Rem., 7: 160–165.
  63. Ostad, S.N., Soodi, M., Shariffzadeh, M., Khorshidi, N. and Marzban, H. (2001). The effect of fennel essential oil on uterine contraction as a model for dysmenorrhea, pharmacology and toxicology study. J. Ethnopharmaco., 76: 299–304.
  64. Ozbek, H., _gras, U., Dülger, S., Bayram, H., Tuncer, I. and Öztürk, I. G. (2003). Hepatoprotective effect of Foeniculum vulgare essential oil. Fitoterapia, 74: 317-319.
  65. Parthasarathy, V. A., K. Kandinnan and V. Srinivasan (2008). “Fenugreek”. Organic Spices. New India Publishing Agencies. p. 694.
  66. Penna, S. C., Medeiros, M. V., Aimbire, F. S. C., Faria-Neto, H. C. C., Sertie, J. A. A. and Lopes-Martins, R. A. B. (2003). Anti- inflammatory effect of the hydralcoholic extracts of Zingiber officinale rhizomes on rat paws and skin edema. Phytome, 10(5): 381-385.
  67. Pliny, Natural History, Loeb Classical Library, Vol. VI, Harvard University Press, (1942), pp, 111 and 113.
  68. Pradhan, M., Sribhuwaneswari, S., Karthikeyan, D., Minz, S., Sure, P. and Chandu, A. N. (2008). In-vitro cytoprotection activity of Foeniculum vulgare and Helicteres isora in cultured human blood lymphocytes and antitumour activity against B16F10 melanoma cell line. Res. J. Phar. and Tech., 1(14): 450-452.
  69. Pruthi, JS. (1992). Spices and Condiments. National Book Trust. 4th ed. New Delhi.
  70. Qian, D. S. and Liu, Z. S. (1992). Pharmacologic studies of antimotion sickness actions of ginger
  71. Raghuram, T.C., Sharma, R.D., Sivakumar, B. and Sahay, B.K. (1994). Effect of fenugreek seeds on intravenous glucose disposition in non- insulin dependent diabetic patients. Phytotherapy Res., 8: 83–86.
  72. Raj Kumar, R. (2004). Studies on estrus induction efficiency of certain medicinal plants and homeopathic drugs in anoestrus cows. M.V.sc. thesis submitted to IVRI, Deemed University, Izatnagar, U.P. and India.
  73. Rather, M. A., Dar, B. A., Sofi, S. N., Bhat, B. A., and Qurishi, M. A. (2016). Foeniculum vulgare: A comprehensive review of its traditional use, phytochemistry, pharmacology, and safety. Arabian Journal of Chemistry, 9, S1574-S1583.
  74. RaviKumar, P. and Anuradha, C.V. (1999). Effect of fenugreek seeds on blood lipid peroxidation and antioxidants in diabetic rats. Phytotherapy Res., 13 (3): 197-201.
  75. Reynolds, E.F.J. (1982). Essential Oils and Aromatic Carminatives, Martindale, the Extra Pharmacopeia, 28th ed. Royal Pharmac.l Society, London, pp. 670-676.
  76. Ribes, G., Sauvaire, Y., Baccou, J. C., Valette, G., Chenon, D., Trimble, E. R. and Loubatières-Mariani, M. M. (1984). Effects of fenugreek seeds on endocrine pancreatic secretions in dogs. Annals of Nutrition and Metabolism, 28(1), 37-43. 
  77. Ruberto, G., Baratta, M. T., Deans, S. G. and Dorman, H. J. D. (2000). Antioxidant and antimicrobial activity of Foeniculum vulgare and Crithmum maritimum essential oils. Planta Medica, 66: 687-693.
  78. Salie, F., Eagles, P.F.K., Leng and H.M.J., (1996). Primary antimicrobial screening of four South African Asteraceae species. J. Ethanopharmacol. 52, 27–33. 
  79. Sapra, B. Gupta, S. and Tiwary, A.K. (2000). Role of volatile oil pretreatment and skin cholesterol on permeation of ion-paired diclofenac sodium. Indian J Exp Biol., 38(9):895-900.
  80. Shani, J., Goldschmied, A., Joseph, B., Aharonson, Z. and Sulman, F.G. (1974). Hypoglycaemic effect of Trigonella foenum graecum and Lupinus termis (Leguminosae) seeds and their major alkaloids in alloxan-diabetic and normal rats. Archives Inter. Pharmacody.Thera., 210: 27–37. 
  81. Sharma, R. D., Raghuram, T. C. and Rao, N. S. (1990). Effect of fenugreek seeds on blood glucose and serum lipids in type I diabetes. Eur J Clin Nutr, 44(4), 301-6.
  82. Sharma, R.D. (1986). Effect of fenugreek seed and leaves on blood glucose and serum insulin responses in human subject. Nutr. Res., 6: 1353–1364.
  83. Shirin, Adel P. R. and Jamuna Prakash (2010). Chemical composition and antioxidant properties of ginger root (Zingiber officinale). Journal of Medicinal Plants Research, 4 (24), pp. 2674-2679.
  84. Shobana, S. and Naidu, K.A., (2000). Antioxidant activity of selected Indian spices. Prostagland. Leukot. Essent. Fatty Acids 62: 107–110. 
  85. Shojaaddini M, Moharramipour S and Sahaf B. (2008). Fumigant toxicity of essential oil from Carum copticum against Indian meal moth, Plodia interpunctella. J Plant Prot Res. 48 (4):411–19.
  86. Singh MP, Panda H (2005). Medicinal Herbs with Their Formulations Volume 1. Daya Publishing House, Delhi, India, pp 97-100, 408-410.
  87. Singh, G., Kapoor, I. P. S., Singh, P., de Heluani, C. S., de Lampasona, M. P. and Catalan, C. A. (2008). Chemistry, antioxidant and antimicrobial investigations on essential oil and oleoresins of Zingiber officinale. Food and Chemical Toxicology, 46 (10), 3295-3302.
  88. Singh, G., Kiran, S., Marimuthu, P., Isidorov, V. and Vinogorova, V. (2008). Antioxidant and antimicrobial activities of essential oil and various oleoresins of Elettaria cardamomum (seeds and pods). Journal of the Science of Food and Agriculture, 88 (2), 280-289. 
  89. Singh, G., Maurya, S., De Lampasona, M. P. and Catalan, C. (2006). Chemical constituents, antifungal and antioxidative potential of Foeniculum vulgare volatile oil and its acetone extract. Food control, 17 (9): 745-752.
  90. Sordillo, L.M. (2005). Factors affecting mammary glad immunity and mastitis susceptibility. Liv. Prod. Sci. 80:1851-1865.
  91. Stoilova, I., Krastanov, A., Stoyanova, A., Denev, P. and Gargova, S. (2007). Antioxidant activity of a ginger extracts (Zingiber officinale). Food chemistry, 102 (3), 764-770. 
  92. Suneetha, W.J. and Krishnakantha, T.P. (2005). Cardamom extract as inhibitor of human platelet aggregation. Phytother Res., 19 (5):437-440. 
  93. Sur, P., Das, M., Gomes, A., Vedasiromoni, J.R., Sahu, N.P., Banerjee, S., Sharma, R.M. and Ganguly, D.K., (2001). Trigonella foenum-graecum (fenugreek) seed extract as an antineoplastic agent. Phytother. Res., 15: 257–259.
  94. Taranalli, A.D. and Kuppast, I.J. (1996). Study of wound healing activity of seeds of Trigonella foenum-graecum in rats. Ind. J. Pharm. Sci., 58: 117–119.
  95. Thomas JE, Bandara M, Lee EL, Driedger D and Acharya S (2011) Biochemical monitoring in fenugreek to develop functional food and medicinal plant variants. N Biotechnol 28: 110-117.
  96. Thomson, M., Al-Qattan, K. K., Al-Sawan, S. M., Alnaqeeb, M. A., Khan, I. and Ali, M. (2002). The use of ginger (Zingiber officinale) as a potential anti-inflammatory and antithrombotic agent. Prostaglandins, leukotrienes and essential fatty acids, 67(6), 475-478. 
  97. Tognolini, M., Ballabeni, V., Bertoni, S., Bruni, R., Impicciatore, M. and Barocelli, E. (2007). Protective effect of Foeniculum vulgare essential oil and anethole in an experimental model of thrombosis. Pharmacol. Res., 56: 254–260.
  98. Ugulu, I., Baslar, S., Yorek, N. and Dogan, Y. (2009). The investiga tion and quantitative ethnobotanical evaluation of medicinal plants used around Izmir province, Turkey. J. Med. Plants Res., 3(5): 345-367.
  99. Vaghasiya, M.P. (2001). Retention of placenta. Honey Bee, 12: 26. 
  100. Wen-Rui Diao, Qing-Ping Hua, Hong Zhang, Jian-Guo Xu. (2014). Chemical composition, antibacterial activity and mechanism of action of essential oil from seeds of fennel (Foeniculum vulgare Mill). Food Control, 35: 109-116. 
  101. Zaman, M. A., Iqbal, Z., Abbas, R. Z., Khan, M. N., Muhammad, G., Younus, M. and Ahmed, S. (2012). In vitro and in vivo acaricidal activity of a herbal extract. Veterinary Parasitology, 186 (3), 431-436.

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