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The role of pheromones in farm animals - A review

DOI: 10.18805/ag.v38i02.7939    | Article Id: R-1652 | Page : 83-93
Citation :- The role of pheromones in farm animals - A review .Agricultural Reviews.2017.(38):83-93

P.M. Kekan*, S.D. Ingole, S.D. Sirsat, S.V. Bharucha, S.D. Kharde and A.S. Nagvekar

drprakash73@gmail.com
Address :

Bombay Veterinary College (MAFSU), Parel– 400 012, Mumbai, India.

Submitted Date : 29-09-2016
Accepted Date : 14-02-2017

Abstract

Pheromones are found throughout the living world and are a primal form of communication. These chemical messengers are transported outside the body and have a direct developmental effect on hormone levels and/or behaviour. The pheromones play an important role in animal behavior and reproductive processes. This review article aims to highlight the role of pheromones of farm animals. The pheromone signals are known to have a potential role in animal reproduction and management. The sources of chemosignals are urine, feces, vaginal secretions, saliva, and specialized scent glands including the odor produced from hair and wool. Pheromones can act as a marker to detect estrus where its detection is a problem and for diagnosing early pregnancy in farm animals. The potential implication of pheromones on improving sexual desire in male is also important. There is huge scope of application of pheromones once it is characterized and synthesized chemically.

Keywords

Biostimulation Farm animal Pheromones Reproduction.

References

  1. Alberio, R. H., Schiersmann, G., Carou, N. and Mestre, J. (1987). Effect of teaser bull on ovarian and behavioural activity of suckling beef cows. Anim. Reprod. Sci., 14: 263-272.
  2. Albone, E.S., Blazquez, N. B., French, J., Long, S. E. and Perry,k G.C. (1986). Mammalian semiochemistry: issues and futures, with some examples from a study of chemical signaling in cattle. In Duval.D.,Muller-Schwarze. D. and Silverstein.R.M. (eds), Chemical Signals in Vertebrates. Plenum Press, New York., 4:27-36.
  3. Archunan G. (2009). Vertebrate pheromones and their biological importance. Indian J. Exper. Bio., 12: 227–239.
  4. Archunan G. and Rajanarayanan, S. (2010). Composition for enhancing bull sex libido. Indian Patent No. 244991.
  5. Archunan G. and Rameshkumar, K. (2012). 1-Iodoundecae an estrus indicating urinary chemosignal in bovine (Bos taurus). J. Vet. Sci. Tech., 3: 121–123.
  6. Bendaall, J.G. (2001). Aroma compounds of fresh milk from New Zealand cows fed different diets. J. Agricult. Food Chem. 49: 4825–32.
  7. Berardinelli, J.G., Fogwell, R.L. and Inskeep, E.K. (1978). Effect of electrical stimulation or presence of a bull on puberty in beef heifers. Theriogenol., 9:133.
  8. Berardinelli, J. G. and Joshi, P. S. (2005). Initiation of postpartum luteal function in primiparous restricted-suckled beef cows exposed to a bull or excretory products of bulls or cows. J. Anim. Sci., 83: 2495-2500.
  9. Blazquez, N.B., French, M.J., Long, S.E. and Perry, G.C. (1988b). A pheromonal function for the perineal skin glands in the cow. Vet. Rec. 123: 49–50.
  10. Booth, W. D. (1984). Sexual dimorphism involving steroidal pheromones and their binding protein in the submaxillary salivary gland of the Göttingen miniature pig. J. Endocrinol., 100:195-202. 
  11. Brooks, P. H. and Cole, D. J. (1970). The effect of the presence of boar on the attainment of puberty in gilts. J. Reprod. Fertil. 23: 435–440. 
  12. Buda, V., Mozûraitis, R., Kutra, J. and Karlson, A. B. K. (2012). p-Cresol: A sex pheromone component identified from the estrous urine of mares. J. Chem. Ecol. 38: 811–813.
  13. Cozzi, A., Lafont-Lecuelle, C., Articlaux, F., Monneret, P., Bienboire-Frosini, C., Bougrat, L. and Pageat, P. (2012). Impact of maternal equine appeasing pheromone (EAP) during a short term transport in saddle horses. - IRSEA Research Institute Semiochemistry and Applied Ethology. 
  14. Chenoweth, P. J. (1983). Reproductive management procedures in control of breeding. Anim. Prod. Australia 15: 28-31.
  15. Claus, R. (1979). Pheromone bei Säugetieren unter besonderer Berücksichtigung des Ebergeruchsstoffes und seiner Beziehungen zu anderen Hodensteroiden. Beiheft 10: Fortschritte in der Tierphysiologie und Tierernahrung. Hamburg, Berlin: Paul Parey.
  16. Cohen-Tannoudji, J., Einhorn, J. and Signoret, P. (1994). Ram sexual pheromone: First approach of chemical identification. Physiol. Behav., 56: 955–961.
  17. Crowell-Davis, S. and Houpt, K. A. (1985). The ontogeny of flehmen in horses. Equine. Vet. J., 33: 739–45.
  18. Custer, E. E., Berardinelli, J. G., Short, R. E., Wehrman, M. and Dair, R. A. (1990). Postpartum interval to estrus and patterns of LH and progesterone in first-calf suckled beef cows exposed to mature bulls. J. Anim. Scie., 68: 1370–    1377.
  19. Cushwa, W. T., Bradford, G. E., Stabenfeldt, G.H., Berger, Y. M. and Dally, M. R. (1992). Ram influence on ovarian and sexual activity in anestrous ewes, effects of isolation of ewes from rams before joining and date of ram introduction. J. Anim. Sci., 70: 1195-1200.
  20. Danell, B., Gopakumar, N., Nair, M. C. S. and Rajagopalan, K. (1984). Heat symptoms and detection in Surti buffalo heifers. Ind. J. Anim. Res., 5: 1–7.
  21. Denhard, M., Claus, R., Pfeiler, S. and Schopper, D. (1991). Variation in estrus-related odours in the cow and its dependency on the ovary. Theriogenol., 35: 645–652.
  22. Delgadillo, J. A., Gelez, H., Ungerfeld, R., Hawken, P. A. R. and Martin, G. B. (2009). The male effect in sheep and goats-    Revisiting the dogmas. Behav. Brain Res., 200: 304-314.
  23. Dobson, H. and Kamonpatana, M. (1986). A review of female cattle reproduction with special reference to comparison between buffaloes, cows and Zebu. Journal of Reproduction and Fertility 77: 1–36.
  24. Dozier, L. A. and Pritt, J. H. (1987). Sexual behaviour of Holstein cows treated with progesterone and oestradiol benzoate. J. Dairy Sci., 70: 205.
  25. Dyck, G.W. (1988). Factors influencing sexual maturation, puberty and reproductive efficiency in the gilt. Can. J. Anim. Sci., 68: 1-13.
  26. Falewee, C. (2006). Effect of a synthetic equine maternal pheromone during a controlled fear-eliciting situation. Appl. Anim. Behav. Sci., 101: 144-153. 
  27. Fernandez, D. L. and Berardinelli, J. G., Short,. R. E. and Adair, R. (1996). Acute and chronic changes in luteinizing hormone secretion and postpartum interval to estrus in first-calf suckled beef cows exposed continuously or intermittently to mature bulls. J. Anim. Sci., 74: 1098–1103.
  28. Garcia, M. C., McDonnell, S. M. and Kenney, R. M. (1986). Bull sexual behaviour tests: stimulus cow affects performance. Appl. Anim. Behav. Sci. 16: 1–10.
  29. Gaultier, E., Bonnafous, L., Bought, L., Lafont, C. and Pageat, P. (2005). Comparison of the efficacy of a synthetic dog-    appeasing pheromone with clomiraine for the treatment of separation-related disorders in dogs. Vet. Rec.,156: 533–538.
  30. Gelez, H. and Fabre-Nys, C. (2004). The “male effect” in sheep and goats: a review of the respective roles of the two olfactory systems. Horm. Behav., 46: 257–271.
  31. Gokuldas, P. P., Yadav, M. C., Kumar, H., Singh, G., Mahmood, S. and Tomar, A. K. S. (2010). Resumption of ovarian cyclicity and fertility response in bull exposed postpartum buffaloes. Anim. Reprod. Sci. 121: 236-241.
  32. Griffith, C. A., Steigerwald, E. S. and Buffington, A. T. (2000). Effects of a synthetic facial pheromone on behavior of cats. J. American Vet. Med. Asso., 217: 1154–1156.
  33. Hawken, P.A.R. and Martin, G.B. (2012). Sociosexual stimuli and gonadotropin-releasing hormone/luteinizing hormone secretion in sheep and goats. Domestic Anim. Endocrinol., 43: 85-94
  34. Hillyer, G. M. (1976). An investigation using a synthetic porcine pheromone and the effect on days from weaning to conception. Vet. Rec., 98: 93-94.
  35. Hughes, P. E. and Cole, D. J. A. (1976). Reproduction in the gilt. 2. The influence of gilt age at boar introduction on the attainment of puberty. Anim. Prod. 23: 89-94.
  36. Ichimaru, T., Mogi, K., Ohkura, S., Mori, Y. and Okamura, H. (2008). Exposure to ram wool stimulates gonadotropin-    releasing hormone pulse generator activity in the female goat. Anim. Reprod. Sci., 106: 361-368.
  37. Izard, M. K. and Vandenbergh, J. G. (1982). The effect of bull urine on puberty and calving date in crossbreed heifers. J. Anim. Sci. 55: 1160–68.
  38. Izard, M. K. (1983). Pheromones and reproduction in domestic animals. In: Pheromones and Reproduction in Mammals. Vandenbergh JG (Ed.). New York Academic Press, pp. 253-285.
  39. Johnston, R. E. and Lee, N. A. (1976). Persistence of the odor deposited by two functionally distinct scent marking behaviours of golden hamster. Behav. Biol. 16: 199–210.
  40. Karlson P, Luscher M. (1959). ‘Pheromones’: a new term for a class of biologically active substances. Nature 183: 55–6.
  41. Kaiser, H., Gilman, S. D., Stahl, U. and Jahne, H. (1980). Use of synthetic boar odour to stimulate reproductive performance in sows. Monatshefte fur Vet., 35: 863-866.
  42. Karthikeyan, K. and Archunan, G. J. (2013). Gas chromatographic mass spectrometric analysis of estrus-specific volatile compounds in buffalo vaginal mucus after initial sexual foreplay. Buff. Sci., 2: 1–7.
  43. Keller, M. and Meurisse, M., Lévy, F. (2004). Mapping the neural substrates involved in maternal responsiveness and lamb olfactory memory in parturient ewes using Fos imaging. Behav. Neurosci. 118: 1274–1284.
  44. Knight, T. W. and Lynch, P. R. (1980). The source of ram pheromones that stimulate ovulation in the ewe. Anim. Reprod. Scie. 3: 133-136.
  45. Landolt, J.P. (1997). Sex attractant and aggregation pheromones of male phytophagous insects. American Entomol., 43: 12–22.
  46. Landaeta-Hernández, A. J, Giangreco, M., Meléndez, P., Bartolomé, J., Bennet, F., Rae, D. O., Hernández, J. and Archbald, L. F. (2004). Effect of biostimulation on uterine involution, early ovarian activity and first postpartum estrous cycle in beef cows. Theriogenol., 61: 1521- 1532.
  47. Lévy, F., Keller, M. and Poindron, P. (2004). Olfactory regulation of maternal behavior in mammals. Horm. Behav., 46: 284–302.
  48. Levy, F. and Fleming, A. S. (2006). The neurobiology of maternal behavior in mammals. In: Marshall P.J, Fox N.A, editors. The Development of Social Engagement. Neurobiological Perspectives. Oxford University Press; New York: pp. 197–246.
  49. Levine, E. D. and Mills, D. S. (2008). Long term follow-up of the efficacy of a behavioural treatment programme for dogs with firework fears. Vet. Rec., 162:657–659.
  50. Lurette, A., Freret, S., Chanvallon, A., Experton, C., Frappat, B., Gatien, J., Dartois, S., Martineau, C., Danvic, C., Ribaud, D., Fatet, A. and Pellicer-Rubio, M. (2016). Management o duction in sheep and goats, conventional and organic farming production systems: inventory of practices, interest and acceptability of new management tools in six production areas in France. INRA Prod. Anim. 29(3): 163-184.
  51. Macmillan, K. L., Allison, A. J. and Struthers, G. A. (1979). Some effects of running bulls with suckling cows or heifers during the premating period. N. Z. J. Exp. Agric. 7:121.
  52. McClintock, M.K. (1978). Estrous synchrony and its mediation by airborne chemical communication (Rattus norvegicus). Horm. Behav., 10: 264-276.
  53. Meurisse, M., Chaillou, E. and Lévy, F. (2009). Afferent and efferent connections of the cortical and medial nuclei of the amygdala in sheep. J. Chem. Neuroanat., 37: 87–97.
  54. Mostafa, T., Khouly, G. El. and Hassan, A. (2012). Pheromones in sex and reproduction: Do they have a role in humans?. J Adv. Res., 3: 1–9.
  55. Nowak, R., Keller, M., Levy, S. (2011). Mother-young relationship in sheep: A model for a multidisciplinary approach of the study of attachment in mammals. J. Neuroendocrinol., 23: 1042–1053.
  56. O´Riordan, E. G. and Hanrahan, J. P. (1989). Advancing first estrus in ewe lambs. Farm. Food. Res., 20: 25-27.
  57. Pageat, P. and Teyssier, Y. (1998). Usefulness of a porcine pheromone analogue in the reduction of aggressions between weanlings on penning; behavior study. Congr. Inter. Pig Vet. Society., 413.
  58. Pageat, P. (2001). Pig appeasing pheromones to decrease stress, anxiety and aggressiveness. US Patent n°6 169:113.
  59. Pageat, P. and Gauliter, E. (2003). Current research in canine and feline pheromones. Vet. Clinical. Small Anim., 33: 187-    211.
  60. Patterson, R.L.S. (1966). 5a-androst-16- en–3-one: compound responsible for taint in boar fat. J. Sci. Food Agr. 19 : 31–    37.
  61. Patterson, R.L.S. (1968). Identification of 3a-hydroxy-5a-androst- 16-en-ol as the musk odour component of boar submaxillary salivary gland and its relationship to the sex odour taint in pork meat. J. Sci. Food Agr. 19 :434–438.
  62. Patra, M. K., Kumar, H. and Barman, P. (2007). Biostimulation: an alternative approach to improve reproductive efficiency in farm animals. Livestock Inter., 11: 6-9.
  63. Patra, M. K., Barman, P. and Kumar, H. (2012). Potential application of pheromones in reproduction of farm animals- A Review. Agricult. Reviews., 33: 82-86.
  64. Patel, H.P. and Gohil, P.V. (2014). Pheromones in Animal World: Types, Detection and its Application Sch. Acad. J. Biosci., 2: 22-26
  65. Porter, R. H., Levy, F., Poindron, P., Litterio, M., Schaal, B. and Beyer, C. (1991). Individual olfactory signatures as major determinants of early maternal discrimination in sheep. Dev. Psychobiol., 24: 151–158.
  66. Preti, G. (1984). Method for detecting bovine estrus by determining methyl heptanol concentrations in vaginal secretions. US Patent No. 4:467,814.
  67. Rameshkumar, K. (2000). India: Bharathidasan University; Chemical characterization of bovine (Bos taurus) urine with special reference to reproductive behavior. Ph.D. thesis.
  68. Rajanarayanan, S. and Archunan, G. (2004). Occurrence of flehmen in male buffaloes (Bubalus bubalis) with special reference to estrus. Theriogenol., 61: 861–866.
  69. Rajanarayanan, S. and Archunan, G. (2011). Identification of urinary sex pheromones in female buffaloes and their influence on bull reproductive behaviour. Res. Vet. Sci. 91: 301–305.
  70. Rampin, O., Jerome, N., Briant, C., Boué, F. and Maurin, Y. (2006). Are oestrous odors species specific? Behav. Brain. Res., 172: 169–72.
  71. Rasmussen, L. E. L., Schmidt, M. J., Henneous, R., Groves, D. and Daves, G. D. (1982). Asian bull elephants: flehmen-like responses to extractable components in female elephant estrous urine. Sci., 217: 159–62.
  72. Rasmussen, L. E. L., Lee, T. D., Roelofs, W. L., Zhang, A. and Jr. Daves G. D. (1996). Insect heromone in elephants. Nat., 379: 684.
  73. Rasmussen, L. E. L., Lee, T. D., Zhang, A., Roelofs, W. L. and Jr. Daves, G. D. (1997). Purification, identification concentration and bioactivity of (2)-7-dodecen-1-yl-acetate: sex pheromone of the female asian elephant, Elephas maximus. Chem. Senses., 22:417–38.
  74. Rekwot, P. I., Ogwy, D. and Oyedipe, E. (2000). Influence of bull stimulation, season and parity on resumption of ovarian activity of zebu (Bos indicus) cattle following parturition. Anim. Reprod. Sci., 63: 1-11.
  75. Rekwot, P. I., Ogwu, D., Oyedipe, E. O. and Sekoni, V. O. (2001). The role of pheromones and biostimulation in animal reproduction. Anim. Reprod. Sci., 65: 157–70.
  76. Rivard, G. and Klemm, W. R. (1989). Two body fluids containing bovine estrous pheromone(s). Chem. Senses., 14: 273-    279.
  77. Riley, R., Grogan, E., McDonnell, S. (2002). Philadelphia: University of Pennsylvania; Evaluation of usefulness if equine appeasing pheromone in gentling of foals and yearlings. Thesis.
  78. Roberson, M.S., Ansotegui, R.P., Berardinelli, J.G., Whitman, R.W. and McInerney, M.J. (1987). Influence of biostimulation by mature bulls on occurrence of puberty in beef heifers. J. Anim. Sci. 64:1601-1605.
  79. Sambraus, H.H. and Waring, Z. (1975). Effect of urine from estrous cows on libido in bulls. Zoo. Saug. 40: 49–54.
  80. Sankar, R. and Archunan, G. (2004). Flehmen response in bull: role of vaginal mucus and other body fluids of bovine with special reference to oestrus. Behav. Proces., 67: 81–86.
  81. Scaloni, A., Paolini, S., Brandazza, A., Fantacci, M., Bottiglieri, C., Marchese, S., Navarrini, A., Fini, C., Ferrara, L. and Pelosi, P. (2001). Purification, cloning and characterization of odorant- and pheromone- binding proteins from pig nasal epithelium. Cell. Mol. Life. Sci. 58: 823–34.
  82. Shelton, M. (1960). Influence of the presence of a male goat on the initiation of estrous cycling and ovulation of angora does. J. Anim. Sci. 19: 368.
  83. Shorey, H. H. (1976). Animal Communication by Pheromones. Academic Press, New York.
  84. Short, R.E., Bellows, R.A., Staigmiller, R.E., Berardinelli, J.G. and Custer, E.E. (1990). Physiological mechanisms controlling anestrus and infertility in postpartum beef cattle. J. Anim. Sci., 68:799–816.
  85. Signoret, J.P. and du Mesnil du Buisson, F. (1961). Etude du comportement de la truie en oestrus. Proceeding of 4th International Congress of Animal Reproduction. The Hague., 2:171–175.
  86. Signoret, J.P. and Mauleon, P. (1962). Action de l’ablation des bulbes olfactifs sur le mécanismes de la reproduction chez la truie. Annales de Biologie Animale, Biochimie, Biophysique., 2: 167–74.
  87. Signoret, J.P. (1970). Reproductive behavior of pigs. J. Reprod. Fertil., 11: 105–117.
  88. Signoret, J.P. (1991). Sexual pheromones in the domestic sheep: importance and limits in the regulation of reproductive physiology. J. Steroid Biochem. Molec. Biol., 39: 639-645.
  89. Sobel, N. and Brown, W.N. (2001). The scented brain: pheromonal responses in humans. Neuron., 31:512–4. 
  90. Temple, D., Barthélémy, H., Mainau, E., Cozzi, A., Amat, M., Canozzi, M.E. and Pageat, P., Manteca, X. (2016). Preliminary findings on the effect of the pig appeasing pheromone in a slow releasing block on the welfare of pigs at weaning. Porcine Health Management., 2: 13.
  91. Thompson, L.H. and Savage, J.S. (1978). Age at puberty and ovulation rate in gilts in confinement as influenced by exposure to a boar. J. Anim. Sci., 47: 1141-1144.
  92. Thomas, S., Becker, W.C. and Wiebold, J.L. (1988). Influence of various progesterone levels on behavioural oestrus in ovariectomized cows. Proceedings of Society of Anim. Sci., 36: 368–70.
  93. Tilbrook, A.J and Cameron, A.W.N. (1989). Ram mating preferences for wooly rather than recently shorn ewes. Appl. Anim. Behav. Sci. 24: 301–312.
  94. Ungerfeld, R. and Silva, L. (2004). The presence of normal vaginal flora is necessary for normal sexual attractiveness of estrous ewes. Appl. Behav. Sci., 93: 245–250.
  95. Ungerfeld, R. (2007). Socio-sexual signaling and gonadal function: Opportunities for reproductive management in domestic ruminants. In: Reproduction in Domestic Ruminants VI. Juengel JI, Murray JF, Smith MF (Eds,). Nottingham University Press, Nottingham, UK. pp. 207-221.
  96. Rajanarayanan, S. and Archunan, G. (2011). Identification of urinary sex pheromones in female buffaloes and their influence on bull reproductive behaviour. Res. Vet. Sci. 91: 301–305.
  97. Rampin, O., Jerome, N., Briant, C., Boué, F. and Maurin, Y. (2006). Are oestrous odors species specific? Behav. Brain. Res., 172: 169–72.
  98. Rasmussen, L. E. L., Schmidt, M. J., Henneous, R., Groves, D. and Daves, G. D. (1982). Asian bull elephants: flehmen-like responses to extractable components in female elephant estrous urine. Sci., 217: 159–62.
  99. Rasmussen, L. E. L., Lee, T. D., Roelofs, W. L., Zhang, A. and Jr. Daves G. D. (1996). Insect heromone in elephants. Nat., 379: 684.
  100. Rasmussen, L. E. L., Lee, T. D., Zhang, A., Roelofs, W. L. and Jr. Daves, G. D. (1997). Purification, identification concentration and bioactivity of (2)-7-dodecen-1-yl-acetate: sex pheromone of the female asian elephant, Elephas maximus. Chem. Senses., 22:417–38.
  101. Rekwot, P. I., Ogwy, D. and Oyedipe, E. (2000). Influence of bull stimulation, season and parity on resumption of ovarian activity of zebu (Bos indicus) cattle following parturition. Anim. Reprod. Sci., 63: 1-11.
  102. Rekwot, P. I., Ogwu, D., Oyedipe, E. O. and Sekoni, V. O. (2001). The role of pheromones and biostimulation in animal reproduction. Anim. Reprod. Sci., 65: 157–70.
  103. Rivard, G. and Klemm, W. R. (1989). Two body fluids containing bovine estrous pheromone(s). Chem. Senses., 14: 273-    279.
  104. Riley, R., Grogan, E., McDonnell, S. (2002). Philadelphia: University of Pennsylvania; Evaluation of usefulness if equine appeasing pheromone in gentling of foals and yearlings. Thesis.
  105. Roberson, M.S., Ansotegui, R.P., Berardinelli, J.G., Whitman, R.W. and McInerney, M.J. (1987). Influence of biostimulation by mature bulls on occurrence of puberty in beef heifers. J. Anim. Sci. 64:1601-1605.
  106. Sambraus, H.H. and Waring, Z. (1975). Effect of urine from estrous cows on libido in bulls. Zoo. Saug. 40: 49–54.
  107. Sankar, R. and Archunan, G. (2004). Flehmen response in bull: role of vaginal mucus and other body fluids of bovine with special reference to oestrus. Behav. Proces., 67: 81–86.
  108. Scaloni, A., Paolini, S., Brandazza, A., Fantacci, M., Bottiglieri, C., Marchese, S., Navarrini, A., Fini, C., Ferrara, L. and Pelosi, P. (2001). Purification, cloning and characterization of odorant- and pheromone- binding proteins from pig nasal epithelium. Cell. Mol. Life. Sci. 58: 823–34.
  109. Shelton, M. (1960). Influence of the presence of a male goat on the initiation of estrous cycling and ovulation of angora does. J. Anim. Sci. 19: 368.
  110. Shorey, H. H. (1976). Animal Communication by Pheromones. Academic Press, New York.
  111. Short, R.E., Bellows, R.A., Staigmiller, R.E., Berardinelli, J.G. and Custer, E.E. (1990). Physiological mechanisms controlling anestrus and infertility in postpartum beef cattle. J. Anim. Sci., 68:799–816.
  112. Signoret, J.P. and du Mesnil du Buisson, F. (1961). Etude du comportement de la truie en oestrus. Proceeding of 4th International Congress of Animal Reproduction. The Hague., 2:171–175.
  113. Signoret, J.P. and Mauleon, P. (1962). Action de l’ablation des bulbes olfactifs sur le mécanismes de la reproduction chez la truie. Annales de Biologie Animale, Biochimie, Biophysique., 2: 167–74.
  114. Signoret, J.P. (1970). Reproductive behavior of pigs. J. Reprod. Fertil., 11: 105–117.
  115. Signoret, J.P. (1991). Sexual pheromones in the domestic sheep: importance and limits in the regulation of reproductive physiology. J. Steroid Biochem. Molec. Biol., 39: 639-645.
  116. Sobel, N. and Brown, W.N. (2001). The scented brain: pheromonal responses in humans. Neuron., 31:512–4. 
  117. Temple, D., Barthélémy, H., Mainau, E., Cozzi, A., Amat, M., Canozzi, M.E. and Pageat, P., Manteca, X. (2016). Preliminary findings on the effect of the pig appeasing pheromone in a slow releasing block on the welfare of pigs at weaning. Porcine Health Management., 2: 13.
  118. Thompson, L.H. and Savage, J.S. (1978). Age at puberty and ovulation rate in gilts in confinement as influenced by exposure to a boar. J. Anim. Sci., 47: 1141-1144.
  119. Thomas, S., Becker, W.C. and Wiebold, J.L. (1988). Influence of various progesterone levels on behavioural oestrus in ovariectomized cows. Proceedings of Society of Anim. Sci., 36: 368–70.
  120. Tilbrook, A.J and Cameron, A.W.N. (1989). Ram mating preferences for wooly rather than recently shorn ewes. Appl. Anim. Behav. Sci. 24: 301–312.
  121. Ungerfeld, R. and Silva, L. (2004). The presence of normal vaginal flora is necessary for normal sexual attractiveness of estrous ewes. Appl. Behav. Sci., 93: 245–250.
  122. Ungerfeld, R. (2007). Socio-sexual signaling and gonadal function: Opportunities for reproductive management in domestic ruminants. In: Reproduction in Domestic Ruminants VI. Juengel JI, Murray JF, Smith MF (Eds,). Nottingham University Press, Nottingham, UK. pp. 207-221.
  123. Van den Hurk, Zeist, R., Pheromone Information Centre; Brugakker, Netherlands: 2007. Intraspecific chemical communication in vertebrates with special attention to its role in reproduction.
  124. Vyas, S., Briant, C., Chemineau, P., Le Danvic, C. and Nagnan-Le Meillour, P. (2012). Oestrus pheromones in farm mammals, with special reference to cow. Ind. J. Anim. Sci., 82: 256–267.
  125. Wani, A.A., Dhindsa, S.S., Shafi, T.A., Chowdhary, S.R.A. and Balwinder, K. (2013). The role of phero mones in animal reproduction – a review. Progressive Res., 8: 14-18.
  126. Wierzbowski, S. and Hafez, E.S.E. (1961). Analysis of copulatory reflexes in the stallion. Proceedings of Fourth International Congress Animal Reproduction. The Hague., 2:176–179.
  127. Wyatt, T.D. (2010). Pheromones and signature mixtures: defining species-wide signals and variable cues for individuality in both invertebrates and vertebrates. J. Comparat. Physiol. A 196: 685–700.
  128. Yamazaki, K., Beauchamp, G.K., Curran, M. and Boyse, E.A. (2000). Parent–progeny recognition as a function of MHC odor type identity. In: Proceedings of National Academy of Science. USA. 97: 10500–10502.
  129. Zalesky, D.D., Day, M.L., Winder, M.G., Imakawa, K., Kittok, R.J., D´Occhio, M.J. and Kinder, J.E. (1984). Influence of exposure to bulls on resumption of estrous cycles following parturition in beef cows. J. Anim. Sci., 59: 1135-1139.
     

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