Still birth and mummification in swine-A review 

DOI: 10.18805/ag.v38i02.7943    | Article Id: R-1625 | Page : 121-128
Citation :- Still birth and mummification in swine-A review .Agricultural Reviews.2017.(38):121-128

R. Raguvaran*, P. Sangeetha, G. Prabakar and V. Jadhav Ravindra 

Address :

ICAR-Indian Veterinary Research Institute, Bareilly-243 122, UttarPradesh, India

Submitted Date : 26-05-2016
Accepted Date : 28-04-2017


Mummification is often noticed in pigs compared to other species due to large litter size. The agents responsible for the reproductive failure in sows may lead to a wide range of sequelae, including abortions, stillbirth, mummification, embryonic death. High prolificacy is associated with increased incidence of stillbirths and mummified fetuses. Plethoras of other foetal and maternal factors have been associated with incidence of still birth and mummification. Identification of those risk factors have been associated with stillbirth and mummified fetuses can helps in optimal herd reproductive efficiency


Farrowing Litter size Mummification Still birth Swine.


  1. Alonso-Spilsbury, M., Mota, M.D., Trujillo, O.M.E., Martínez-Burnes, J., Arch, T.E., López-Mayagoitia, A., Ramírez-Necoechea, R., Olmos, H.S.A. (2004). Use of oxytocine in penned sows and its effect on fetal intrapartum asphyxia. Anim. Reprod. Sci. 84: 157–167.
  2. Baxter, E.B., Jarvis, S., D’Eath , R.B., Ross, DW., R obson S.K., Farish, M., Nevison I.M., Lawrence A.B., Edwards. S.A. (2008). Investigating the behavioural and physiological indicators of neonatal survival in pigs. Theriogenology. 9: 773–783.
  3. Baxter, E.B., Jarvis, S., D’Eath , R.B., Ross, DW., Robson S.K., Farish, M., Nevison I.M., Lawrence A.B., Edwards. S.A. (2008). Investigating the behavioural and physiological indicators of neonatal survival in pigs. Theriogenology. 9: 773–783.
  4. Bilkei, G. and Bölcskei, A. (1993).Die Auswirkung der Fütterung im letzten Trächtigkeitsmonat auf die perinatalen Parameter bei verschiedener Körperkondition und Parität der Muttersauen Tierärztl Umschau. 48: 629–635.
  5. Bölcskei, A., Bilkei, G., Biro, O., Clavadetscher, E., Goos, T., Bilkei, H., Wegmuller, S. 1996. The effect of timing of labor induction on the occurrence of congenital myofybrillar hypoplasia – short clinical report. Dtsch. Tierarztl. Wochenschr. 103: 21–23.
  6. Borges, V.F., Bernardi, M.L., Bortolozzo, F.P. and Wentz, I. (2005). Risk factors for stillbirth and foetal mummification in four Brazilian swine herds. Preventive Veterinary Medicine 70: 165–176.
  7. Canario, L., Cantoni, E., Le Bihan, E., Caritez, J.C., Billon, Y., Bidanel, J.P., Foulley, J.L., (2006a). Between-breed variability of stillbirth and its relationship with sow and piglet characteristics. J. Anim. Sci. 84, 3185–3196
  8. Canario, L., Cantoni, E., Le Bihan, E., Caritez, J.C., Billon, Y., Bidanel, J.P. and Foulley, J.L (2006). Between-breed variability of stillbirth and its relationship with sow and piglet characteristics. Journal of Animal Science. 84: 3185-3196.
  9. Canario, L., Roy, N., Gruand, J., Bidanel, J.P., (2006b). Genetic variation of farrowing kinetics traits and their relationships with litter size and perinatal mortality in French Large White sows. J. Anim. Sci. 84: 1053–1058.
  10. Cassar, G., Kirkwood, R.N., Friendship, R. Poljak, Z. (2004). Sow and litter performance following farrowing induction with prostaglandin: effect of adjunct treatments with dexamethasone or oxytocin. J. Swine Health Prod. 13: 81–85.
  11. Cecchinato, A., Bonfatti, V., Gallo, L., Carnier, P., (2008). Survival analysis of preweaning piglet survival in a dry-cured-ham-    producing crossbred line. J. Anim. Sci. 86: 2486–2495
  12. Close, W.H. and Cole, D.J.A. 2000. Nutrition in Sows and Boars. Nottingham University Press, United Kingdom, pp. 1–8.
  13. Cronin, G.M., Schirmer, B.N., McCallum, T.H., Smith, J.A., Butler, K.L. (1993). The effects of providing sawdust to pre-parturient sows in farrowing crates on sow behavior, the duration of parturition and the occurrence of intra-partum stillborn piglets. Appl. Anim. Behav. Sci. 36: 301–315.
  14. Curtis, S.E. (1974). Responses of the piglet to perinatal stressors. J. Anim. Sci. 38: 1031–1036.
  15. Cutler, R.S., Fahy, V.A., Cronin, G.M., Spicer, E.M., (2006). Preweaning mortality. In: Straw, B., Zimmerman, J., D’Allaire, S., Taylor, D. (Eds.), Diseases of Swine. 9th edition. Blackwell Publishing, Ames Iowa, USA, pp, 93–1009.
  16. Damgaard, L.H., Rydhmer, L., Løvendahl, P., Grandison, K. (2003). Genetic parameters for within-litter variation in piglet birth weight and change in within-litter variation during suckling. J. Anim. Sci. 81: 604–610.
  17. Doberenz, J, Birkenfeld, C, Kluge, H, Eder and K (2006). Effects of L-carnitine supplementation in pregnant sows on plasma concentrations of insulin-like growth factors, various hormones and metabolites and chorion characteristics. J.Anim. Phy. Anim. Nut. 90: 11-12. 
  18. Dial, G.D. 1984. Clinical applications of prostaglandins in swine. J. Am. Vet. Med. Assoc.185: 1523–1530.
  19. Dial, G.D., Marsh, W.E, Polson, D.D and Vaillancourt, J.P (1992). Reproductive failure: Differential diagnosis. In: Leman A.D., Straw, B.E, Mengeling, W.L.D Allaire, S. Taylor, D.J. Diseases of Swine. 7th edition Ames, Iowa: Iowa State University Press, pp 88–137.
  20. Distl, O. (2007). Mechanism of regulation of litter size in pigs on the genome level. Reprod. Dom. Anim. 42: 10–16.
  21. Edwards, S.A. (2002). Perinatal mortality in the pig: environmental or physiological solutions? Livest. Prod. Sci. 78: 3–12.
  22. FAO, (2012). Food and Agricultural Organization, http://www.fao.org/docrep/016/i2727e/i2727e.pdf
  23. Fowden, A.L., Giussani, D.A., Forhead, A.J., (2006). Intrauterine programming of physiological systems: causes and consequences. Physiology 21: 29–37.
  24. Fraser, D., Phillips, P.A., Thompson, B.K. (1997). Farrowing behaviour and stillbirth in two environments: an evaluation of the restraint-stillbirth hypothesis. Appl. Anim. Behav. Sci. 55: 51–66.
  25. Glastonbury, J.R.W. (1977). Preweaning mortality in the pig. Austr. Vet. J. 53: 282–286.
  26. Guillemet, R., Hamard, A., Quesnel, H., Père, M.C., Etienne, M., Dourmad, J.Y., Meunier-Salaün, M.C. (2007). Dietary fibre for gestating sows: effects on parturition progress, behaviour, litter and sow performance. Animal. 1: 872–880
  27. Guthrie, H.D. (1985). Control of time of parturition in pigs. J. Reprod. Fertil. Suppl. 33: 229–244.
  28. Hanenberg, E.H.A.T., Knol, E.F., Merks, J.W.M. (2001). Estimates of genetic parameters for reproduction traits at different parities in Dutch Landrace pigs. Livest. Prod. Sci. 69: 179–186.
  29. Hemsworth, P.H., Pedersen, V., Cox, M., Cronin, G.M., Coleman, G.J. (1999). A note on the relationship between the behavioural response of lactating sows to humans and the survival of their piglets. Appl. Anim. Behav. Sci. 65: 43–52.
  30. Herpin, P., Hulin, J.C., Le Dividich, J., Fillaut, M., (2001). Effect of oxygen inhalation at birth on the reduction of early postnatal mortality in pigs. J. Anim. Sci. 79: 5–10.
  31. Herpin, P., Le Dividich, J., Hulin, J.C., Fillaut, M., De Marco, F. and Bertin, R. (1996). Effects of the level of asphyxia during delivery on viability at birth and early postnatal vitality of newborn pigs. J Anim Sci. 74(9): 2067-75.
  32. Holl, J.W. and Robison, O.W. 2003. Results from nine generations of selection for increased litter size in swine. J. Anim. Sci. 81: 624–629.
  33. Holm, B., Bakken, M., Vangen, O., Rekeya, R. 2004. Genetic analysis of litter size, parturition length and birth assistance requirements in primiparous sows using a joint linear-threshold animal model. J. Anim. Sci. 82: 2528–2533.
  34. Holyoake, P.K., Dial, G.D., Trigg, T., King, V.L. 1995. Reducing pig mortality through supervision during the perinatal period. J.Anim. Sci. 73: 3543–3551.
  35. Janczak, A.M., Pedersen, L.J., Rydhmer, L., Bakken, M., (2003). Relation between early fear- and anxiety-related behaviour and maternal ability in sows. Appl. Anim. Behav. Sci. 82: 121–135.
  36. Johnson, R.K., Nielsen, M.K., Casey, D.S. (1999). Responses in ovulation rate, embryonal survival and litter traits in swine to 14 generations of selection to increase litter size. J. Anim. Sci. 77: 541–557.
  37. Kaeoket, K. 2006. The effect of dose and route of administration of Rcloprostenol and the parturient response of sows. Reprod. Domest.Anim. 41: 472–476.
  38. Kemp, B., Soede, N.M., Vesseur, P.C., Helmond, F.A., Spoorenberg, J.H., Frankena, K. (1996). Glucose tolerance of pregnant sows is related to postnatal pig mortality. J. Anim. Sci. 74: 879–885.
  39. Kharouf, A.T., Deligeorgis, S.G., Rogodokis, E. (1991). Sow reproductive characteristics in intensive pig farming and the factors affecting them, 2. Gestation and lactation length, length of sow’s reproductive life, farrowing interval, weaning to conception and weaning to culling interval. Epithe orese Z ootehnik esEpist emes 13: 25–45.
  40. Knol, E.F., Leenhouwers, J.I., van der Lende, T. (2002). Genetic aspects of piglet survival. Livest. Prod. Sci. 78: 47–55.
  41. Koketsu, Y., Sasaki, Y., Ichikawa, H. and Kaneko, K. (2010). Benchmarking in animal agriculture: concepts and applications. Journal of Veterinary Epidemiology. 14: 105-117.
  42. Lawlor, P.G. and Lynch, P. B. (2007). A review of factors influencing litter size in Irish sows. Irish Veterinary Journal. 60: 359-366.
  43. Lawrence, A.B., Petherick, J.C., McLean, K.A., Gilbert, C.L., Chapman, C., Russell, J.A. 1992. Naloxone prevents interruption of parturition and increases plasma oxytocin following environmental disturbance in parturient sows. Physiol. Behav. 52: 917–923.
  44. Le Cozler, Y., Guyomarc’h. C., Pichodo, X., Quinio, P.Y. and Pellois, H. (2002). Factors associated with stillborn and mummifies piglets in high-prolific sows. Animal Research. 51: 261-268.
  45. Leenhouwers, J.I, de Almeida Junior, C.A., Knol, E.F. and van der Lende, T. (2001). Progress of farrowing and early postnatal pig behavior in relation to genetic merit for pig survival. Journal of Animal Science. 79: 1416–1422.
  46. Leenhouwers, J.I., van der Lende, T., Knol, E.F. (1999). Analysis of stillbirth in different lines of pig. Livest. Prod. Sci. 57: 243–253.
  47. Leenhouwers, J.I., Wissink, P., van der Lende, T., Paridaans, H., Knol, E.F. (2003). Stillbirth in the pig in relation to genetic merit for farrowing survival. J. Anim. Sci. 81: 2419–2424.
  48. Livestock Census (19th), (2012).Department of Animal Husbandry, Dairying & Fisheries, Ministry of Agriculture, Government of India.
  49. Lucia Jr, T., Correˆa, M.N., Deschamps, J.C, Bianchi, I., Donin, M.A., Machado, A.C., Meincke, W. and Matheus, J. E. M. (2002). Risk factors for stillbirth in two swine farms in the south of Brazil. Preventive Veterinary Medicine. 53: 285–292.
  50. Machado-Neto, R., Graves, C.N., Curtis, S.E. (1987). .Immunoglobulins in piglets from sows heat-stressed prepartum. J. Anim. Sci. 65: 445–455.
  51. Maes, D., Janssens, G., Delputte, P., Lammertyn, A., de Kruif, A. (2004). Back fat measurements in sows from three commercial pig herds: relationship with reproductive efficiency and correlation with visual body condition scores. Livest. Prod. Sci. 91: 57–67.
  52. MengelingW L, Langer K M and Vorwald A C. (2000).The effect of porcine parvovirus and porcine reproductive and respiratory syndrome virus on porcine reproductive performance. Animal Reproduction Science 60-61: 199–210.
  53. Mosnier, A., Dourmad, J.Y., Etienne, M., Le Floc’h, N., Père, M.C., Ramaekers, P., Sève, B., Van Migen, J., Meunier-Salaün, M.C. (2009). Feed intake in the multiparous lactating sow: its relationship with reactivity during gestation and tryptophan status. J. Anim. Sci. 87: 1282–1291.
  54. Mota-Rojas, D., Martínez-Burnes, J., Alonso-Spilsbury, M., Lopez, A., Ramírez-Necoechea, R., Trujillo-Ortega, M.E., Medina-    Hernandez, F.J., de la Cruz, N.I., Albores-Torres, V., Loredo-Osti, J. (2006). Meconium staining of the skin and meconium aspiration in porcine intrapartum stillbirths. Livest. Sci. 102. 155–162.
  55. Mota-Rojas, D., Martínez-Burnes, J., Trujillo-Ortega, M.E., AlonsoSpilsbury, M., Ramírez-Necoechea, R., Lopez, A. (2002). Effect of oxytocin treatment in sows on umbilical cord morphology, meconium staining, and neonatal mortality of piglets. Am. J. Vet. Res. 63: 1571–1574.
  56. Mota-Rojas, D., Villanueva-García, D., Velazquez-Armenta, E., NavaOcampo, A., Ramírez-Necoechea, R., Alonso-Spilsbury, M., Trujillo, M.E. (2007). Influence of time at which oxytocin is administered during labor on uterine and perinatal death in pigs. Biol. Res. 40: 55–63.
  57. Muirhead, M.R. and Alexander, T.J.L (1997). Managing Pig Health and the Treatment of Disease. A Reference for the Farm. 5M Enterprises, Sheffield, pp. 133–226.
  58. Odehnalova,, S., Vinkler, A., Novak, P., Drabek, J. (2008). The dynamics of changes in selected parameters in relation to different air temperature in the farrowing house for sows. Czech J. Anim. Sci. 53: 195–203.
  59. Petry, D.B., Johnson, R.K. (2004). Responses to 19 generations of litter size selection in the Nebraska Index line. I. Reproductive responses estimated in pure line and crossbred litters. J. Anim. Sci. 82. 1000–1006.
  60. Ramanau, A., Kluge, H., Spilke, J., Eder, K. (2004). Supplementation of sows with l-carnitine during pregnancy and lactation improves growth of the piglets during suckling period through increased milk production. J. Nutr. 134: 86–92.
  61. Oliviero, C., Kokkonen, T., Heinonen, M., Sankari, S., Peltoniemi, O. (2009). Feeding sows with high fibre diet around farrowing and early lactation: Impact on intestinal activity, energy balance related parameters and litter performance. Res. Vet. Sci. 86: 314–319.
  62. Oliviero, C., Heinonen, M., Valros, A., Peltoniemi, O. (2010). Environmental and sow-related factors affecting the duration of farrowing. Anim Reprod Sci. 119: 85–91.
  63. Rehfeldt, C., Nissen, P.M., Kuhn, G., Vestergaard, M., Ender, K., Oksbjerg, N. (2004). Effects of maternal nutrition and porcine growth hormone (pGH) treatment during gestation on endocrine and metabolic factors in sows, fetuses an pigs, skeletal muscle development, and postnatal growth. Domest. Anim. Endocrinol. 27: 267–285.
  64. Rosend, Druet, T., Gogué, J., Canario, L., Bidanel, J.P. (2007). Correlated responses for litter traits to six generations of selection for ovulation rate or prenatal survival in French large white pigs. J. Anim. Sci. 85: 1615–1624.
  65. Ruis, M.A., Te Brake, J.H., Engel, B., Ekkel, E.D., Buist, W.G., Blokhuis, H.J., Koolhaas, J.M. (1997). The circadian rhythm of salivary cortisol in growing pigs: effects of age, gender, and stress. Physiol.Behav. 62: 623–630.
  66. Rydhmer, L., Lundeheim, N., Canario, L. (2008). Genetic correlations between gestation length, piglet survival and early growth. Livest. Sci. 115: 287–293.
  67. Sasaki, Y., Koketsu, Y. (2007). Variability and repeatability in gestation length related to litter performance in female pigs on commercial farms. Theriogenology. 68: 123–127.
  68. Schaefer, A.L., Tong, A.K.W., Sather, A.P., Beltranena, E., Pharazyn, A., Aherne, F.X. (1991). Preparturient diabetogenesis in primiparous gilts. Can. J. Anim. Sci. 71: 69–77
  69. Schneider, L.G, Costi, G, Wentz, I., Bortolozzo, F.P and Borchardt-Neto, G. (2003). Avaliação da mumificaçãofetalsuínaemumagranja industrial. RevistaBrasileira de Reprodução Animal. 27: 678–683.
  70. Segura-Correa J.C., Alzina-López, A. and Solorio-Rive México. 45: 227-236.
  71. Sims, L.D. and Glastonbury, J.R.W. (1996). Neonatal mortality. In: Sims, L.D., Glastonbury, J.R.W. (Eds.), Pathology of the Pig. A Diagnostic Guide. The Pig Research and Development Corporation, Barton, pp. 423–432.
  72. Sims, L.D. and Glastonbury, J.R.W. (1996). Neonatal mortality. In: Sims, L.D., Glastonbury, J.R.W. (Eds.), Pathology of the Pig. A Diagnostic Guide. The Pig Research and Development Corporation, Barton, pp. 423–432.
  73. Sprecher, D.J., Leman, A.D., Dziuk, P.D., Cropper, M., DeDrecker, M. (1974). Causes and control of swine stillbirths. J. Am. Vet. Med. Assoc. 165: 698–701.
  74. Tabeling, R., Schwier, S., Kamphues, J. (2003). Effects of different feeding and housing conditions on dry matter content and consistency of faeces in sows. J. Anim. Physiol. Anim. Nutr. 87: 116–121.
  75. Taverne, M.A.M. and van der Weijden, G.C. (2008). Parturition in domestic animals: targets for future research. Reprod. Domest. Anim. 43: 36–42.
  76. van der Peet-Schwering, C.M.C., Kemp, B., Binnendijk, G.P., den Hartog, L.A., Vereijken, P.F.G., Verstegen, W.A. (2004). Effects of additional starch or fat in late gestating high non starch polysaccharide diets on litter performance and glucose tolerance in sows. J. Anim. Sci. 82: 2964–2971.
  77. van Dijk, A.J., van Rens, B.T.T.M., van der Lende, T., Taverne, M.A.M. (2005). Factors affecting duration of the expulsive stage of parturition and piglet birth intervals in sows with uncomplicated, spontaneous farrowings. Theriogenology. 64: 1573–1590.
  78. van Rens, B.T.T.M., van der Lende, T. (2004). Parturition in gilts: duration of farrowing, birth intervals and placenta expulsion in relation to maternal piglets and placental traits. Theriogenology. 62: 331–352.
  79. Van Borrel, A., Dobson, H., Prunier, A. (2007). Stress, behaviour and reproductive performance in female cattle and pigs. Horm. Behav.52: 130–138.
  80. Van der Lende, T. (2000). Embryonic and fetal mortality in swine: causes, consequences and how to prevent these losses. In: Proceedings of the 7th Simpósio Internacional de Reprodução e Inseminação Artificial emSuýnos, Foz do Iguaçu, Brazil, pp. 243–252.
  81. Vanderhaeghe, C., Dewulf, J., Jourquin, J., de Kruif, A., Maes, D. (2010c). Incidence and prevention of early parturition in sows. Reprod. Domest. Anim.46: 428–435.
  82. Wehrend, A., Stratmann, N., Failing, K., Bostedt, H., (2005). Influence of partus induction on the pH value in the blood of newborn piglets. J. Vet. Med. A. 52: 472–473.
  83. Weldon, W.C., Lewis, A.J., Louis, G.F., Kovar, J.L., Miller, P.S. (1994). Postpartum hypophagia in primiparous sows: II, Effects of feeding level during gestation and exogenous insulin on lactation feed intake, glucose tolerance, and epinephrine-stimulated release of nonesterified fatty acids and glucose. J. Anim. Sci. 72: 395–403
  84. White, K.R., Anderson, D.M., Bate, L.A.(1996). Increasing piglet survival through an improved farrowing management protocol. Can. J. Anim. Sci. 76: 491–495
  85. Wu, M.C., Hentzel, M.D and Dziuk, P.J (1988). Effect of stage of gestation, litter size and uterine space on the incidence of mummified fetuses in pigs. Journal of Animal Science. 66: 3202–3207.
  86. Zaleski, H.M., Hacker, R.R. (1993). Variables related to the progress of parturition and probability of stillbirth in swine. Can. Vet. J. 34: 109–113.

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