Agricultural Reviews

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Agricultural Reviews, volume 35 issue 4 (december 2014) : 299 - 306

APPLICATIONS AND IMPLICATIONS OF MAMMALIAN ANTIMICROBIAL PEPTIDES- A REVIEW

Shahid Hussain, C.S. Mukhopadhyay*, J.S. Arora
1Post Graduate Institute of Veterinary Education and Research, Guru Angad Dev Veterinary and Animal University, Ludhiana-141 001, India
Cite article:- Hussain Shahid, Mukhopadhyay* C.S., Arora J.S. (2024). APPLICATIONS AND IMPLICATIONS OF MAMMALIAN ANTIMICROBIAL PEPTIDES- A REVIEW. Agricultural Reviews. 35(4): 299 - 306. doi: 10.5958/0976-0741.2014.00918.0.

ABSTRACT

Antimicrobial peptides are host defense peptides that are present in members of both Kingdoms Plantae vis-à-vis Animalia. These comprise of a number of structurally diverse peptides which are upto100 amino acid in length. These antimicrobial peptides are part of the inherent innate immune system of the host and are responsible for carrying out diverse activities ranging from killings the invading pathogens, modifying and regulating the immune system in executing these processes. In the immune system they have diverse functions such as acting as chemotaxis, modulation of inflammation, regulation of expression of inflammatory cytokines preventing hypersensitivity. Antimicrobial peptides are presently under trials for development of novel antibiotics which can be used for treatment of multidrug resistant pathogens. Currently different antimicrobial peptides are used as food preservatives and for prevention of microbes, like methicillin resistant S. aureus among others.

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