DETOXIFICATION OF MIMOSINE AND DIHYDROXVPYRIDONE : A REVIEW

Article Id: ARCC4383 | Page : 104-109
Citation :- DETOXIFICATION OF MIMOSINE AND DIHYDROXVPYRIDONE : A REVIEW.Agricultural Reviews.2000.(21):104-109
S.S. Paul
Address : Central Institute For Research on Buffaloes Sub-Campus, Nabha-147201, India

Abstract

Subabul (Leucaena leucocephala) is considered as a miracle tree due to its protein rich foliage (20–30% CP), fast growing and drought tolerant habits. Use of its foliage as animal feed is being limited by presence of a toxic amino acid-mimosine and its metabolites 3, 4 DHP and 2, 3 DHP. Inclusion of subabul leaves on ration of farm animals results in varied response to severe adverse effects. Treatment of subabul leaf meal with mimosine binding agents reduce mimosine toxicity significantly and this seems to be the most effective detoxification method for nonruminants. But for ruminants a new hope has arisen from the discovery of presence of DHP degrading rumen microbes in some regions of the world including Karnal area of India. Such microbes were identified as Clostridium strain 162 in Venezuela; Synergistes jonsii in USA and a strain of Streptococcus bovis in India. This paper reviews the topic and provides an update information about detoxification of mimosine and DHP.

Keywords

References

  1. Akbar, MA and Gupta,PC.(1985).Indian J. Anim. ScL, 55: 54-58.
  2. Allison, M.J. et al:{l990). App.Exp.Microbiol., 56 : 590-594.
  3. Allison, M.J. et al.(1992). Sys.Appl.Microbiol., 15 : 522-529.
  4. Anonymous (1997). N.D.R.I. News., 1 : 1.
  5. Atreja, P.P. et al. (1990). Report on project 'To test the effect of antimetabolites" . NORI, Karnal, India.
  6. Bhaskar, BV et al. (1987). Indian J. Dairy Sci., 40 : 139-141. • ..
  7. Chakraborty, R.P. and Chhabra, A. (1998). Indian J.Anim.Nutr., 5 : 244-247.
  8. Crounce, R.J. et al. (1962). Nature, 94 : 194-195.
  9. Dharamsare, KS. et al. (1991). Indian J.Anim.Nutr., 8: 61-64.
  10. D'Mello, J.P.F. and Taplin, D.E. (1978). World Rev. Anim. Prod., 14: 41-47.
  11. D'Mel!o, J.P.F. and Fraser, KW. (1981). Tropical Agric. (Trinidad)., 23 : 75-78.
  12. D'Mello, J.P.F. and Acamovic, T. (1982). Tropical Agric. (Trinidad)., 59: 329-332.
  13. D'Mello, J.P.F. et al. (1987). Tropical Agric. (Trinidad)., 64 : 33-35.
  14. D'Mello, J.P.F. (1992). Anim. Feed Soi. Techno1., 38: 237-261.
  15. D'Mello, J.P.F. (1994). Amino acid Imbalances,antagonlsm and toxicities. (Ed. 'Mello.J.P.F.D) CAB Int. Wellingford,
  16. Oxon, London.
  17. Dominguez Bello, M.G. and Stewart, C.S. (1991). Appl.Microbiol, 14 : 67-71.
  18. Elliot, R. et al. (1985). Aust. J. Agric. Res., 36 : 867-875.
  19. Feng,D.Y. and Atreja, P.P. (1994)Twenty fourth Int.Dalry Congress,Melbourne,Australia,Abstract Cb 19,P75.
  20. Gowda, D.R. (1984).lndian J. Anim.1'futr., 3 :233-237.
  21. Gupta, B.K. (1988). Indian J. Anim. Nutr., 5: 202-206.
  22. Gupta, H.K (1995). Ph. D. Thesis, NORI, Karnal, India.
  23. Gupta, H.K and Atreja, P.P. (1994) Abstract presented to 24th Int.Dairy Congress, Melbourne, Australia,
  24. Cb 24 p78.
  25. Hammond, A.C. (1989). Am. J. Vet. Res., 50 : 2176·2180.
  26. Hammond, A.C. (1995). J. Anim.SeI., 73 : 1487-1492.
  27. Hegarty, M.P. et al. (1976). Aust. J. Agric. Res., 15 : 153-167.
  28. Hegarty, M.P. et al. (1997). Aust. Vet. J., 52 : 490.
  29. Hussain, J. et a1. (1991). British Poultry Sci., 32 : 131-137.
  30. Jones, R.J. (1973). In: CSIRO,Dlvision of Tropical Agronomy, Annual Report, Townsville, Queensland, Australia,
  31. p.15.
  32. Jones, R.J. (1979). World Anim.Rev., 31: 13-23.
  33. Jones, R.J. and Megarrlty, R.G. (1983). Austr.J.Agric.Res., 34: 781-790.
  34. Jones,R.J. and Megarrlty,R.G.(1986). Austr.Vet.J., 63: 259-262.
  35. . Kharat, S. T. et al. (1985) Indian J. animo Nutr., 2 : 42-44.
  36. Kudo, H. et al. (1989). Japan Ag. Res. quarterly., 23 : 78-80.
  37. Kurar, C. K '~t a1. (1984). Indian J. Anim. Sel., 54 : 420-424.
  38. Vol. 21. No.2. 2000 109
  39. Labadan, M. M. (1969). Phillipp. Agric., 53: 392-401.
  40. Lowry, J. B. (1982). In: Asia-Pacific Region, lORe. Otti'lWi'l. Canada, p 49-54.
  41. Mi'lli, ,I. M. et 01. (1990). Indian J. Anim. Sci., 54 : 420-424.
  42. Meulin. U-ter, et a/. (1984). Archiv. Fur. Guffugelkur.de. 48 : 41-44.
  43. Montagna,w. and Yu, J. S. (1963). Trap. Grasslands., 2: 19-30,
  44. NAS (1977). Leucaena : Promising Forage and Tree crop for the tropics. National Academy of Sciences,
  45. Washington, D.e.
  46. NAS (1981). Leucaena : Promising Forage and Tree crop for the tropics. National Acarlemy of
  47. Sciences, Washington,D.e.
  48. Onwudike, O.e. (1995). Anim. Feed Sci. Technol., 51 : 153-163.
  49. Owen, L.N. (1958) Vet. Record., 70 : 454-457.
  50. Pal, R.N. et 01. (1979). Forageres., 5 : 109-115.
  51. Pathak, P. S. and Pati!, B.D. (1983). In: Leucaena Research In Asia Pacific region, IDRC, Ottawa, Canada, P 83-88.
  52. Paul, S. S. (1996). M.Sc. Thesis, NDRI, Karnal, India.
  53. Paul, S.S. et a/. (1997). In : National Symposium on Feeding Strategies for ecofriendly Animal Production in India.
  54. (Abstracts) IVRI, Izatnagar, Bareilly, UP, India. p .59.
  55. Paul, S. S. et 01. (1999). Indian J.Anim. Nutr., 6: 68-71.
  56. Quirck, M.E eta/. (1998). J. Agric. Sci., 111: 165-170.
  57. Ram, .J.J. et 01. (1994). Tropical Hlth. Prod., 26 : 199-206.
  58. Reis, P.J. eta/. (1975) Aust. J. Bioi. Sci., 28: 495-501.
  59. Ross, E. and Springhall, J.A. (1963). Aust. Vet. J., 39 : 394-397.
  60. Samanta, A.K. (1991). M.Sc. Thesis, NDRI, Karnal, India.
  61. Samanta, A.K. et 01. (1994). Anim. Feed. Sci. Technol., 50 : 157-165.
  62. Serrano, E.P. et 01. (1983). Aust. J. Bioi. Sci., 36: 445-454.
  63. Sharma, T. et a/. (1990). Indian J. Anim. Nutr., 7 : 295-298.
  64. Shukla, P.e. et 01. (1987) Indian ,f. Anim. Nutr., 4 : 207-208.
  65. Shyam, R. et a/. (1990) In Proc.of National Seminar on Sheep and Goat Nutrition i'lnd Pi'lsturp I ltilization, Avikanagi'lr, Rajasthan, p. 139.
  66. Sobal, B.N. et 01. (1978). Trap. Anim. Hlth. Prod., 10: 237-241.
  67. Stunzi, H. et al. (1980) Aust. J. Chem., 33 : 2207-2220.
  68. Tawata, S. et 01. (1986). Sci. Bull. College Agric. Univ., Rykyus, Okinawa, 33 : 87-93.
  69. Tsal, w.e. and Ling, K.H. {1973). J. Chem. Biochem. Soc. 2 : 70-86.
  70. Upadhyay, V.S. et 01. (1974). Indian Vet. J., 51 : 534-537.
  71. Wang, J. et a/. (1992). Practacultural Science 9: 1, 20-22.
  72. Wills, R.B.H. and TangenjaJa, B. (1981). Phytochemistry, 20 : 2017-2018.

Global Footprints