Indian Journal of Animal Research

  • Chief EditorK.M.L. Pathak

  • Print ISSN 0367-6722

  • Online ISSN 0976-0555

  • NAAS Rating 6.50

  • SJR 0.263

  • Impact Factor 0.5 (2023)

Frequency :
Monthly (January, February, March, April, May, June, July, August, September, October, November and December)
Indexing Services :
Science Citation Index Expanded, BIOSIS Preview, ISI Citation Index, Biological Abstracts, Scopus, AGRICOLA, Google Scholar, CrossRef, CAB Abstracting Journals, Chemical Abstracts, Indian Science Abstracts, EBSCO Indexing Services, Index Copernicus
Submit

Research Article

Indian Journal of Animal Research, volume 51 issue 1 (february 2017) : 97-104

Evaluation of aspirin (ASA) in broiler chicken during hot dry summer using zoo technical, molecular and physio-biochemical tools

J.J. Rokade*, S.K. Bhanja, A.S. Shinde, Sajjad, Darshana B. Bhaisare, A.B. Mandal
1<p>Central Avian Research Institute,&nbsp;Izatnagar-243 122, UP, India.</p>
Cite article:- Rokade* J.J., Bhanja S.K., Shinde A.S., Sajjad, Bhaisare B. Darshana, Mandal A.B. (2016). Evaluation of aspirin (ASA) in broiler chicken during hot dry summer using zoo technical, molecular and physio-biochemical tools . Indian Journal of Animal Research. 51(1): 97-104. doi: 10.18805/ijar.v0iOF.6836.

ABSTRACT

The present study was undertaken to evaluate the efficacy of aspirin as anti-heat stressor. Broiler chicks were reared on a standard diet up to 14 days of age. Thereafter, the chicks were randomly distributed into three dietary treatment groups viz., T1 (Control group: Standard diet), T2 (Standard diet with aspirin@250 mg/kg) and T3 (Standard diet with aspirin@500 mg/kg). Each treatment was having five replicates of eight birds per replicate. Experiment was carried out during hot-dry (April-May, 30.0±0.70 to 37.0±1.40C, Rh, %: 58.05±1.32 to 70.11±0.82) summer. Feed intake and live weight gain was comparable among the treatments but FCR, protein and energy efficiency improved significantly (P<0.001) on aspirin supplementation. The relative yield of thymus and bursa at 4th and 6th week of age improved significantly (P<0.05). The percentage of protein, aspartate transaminase (AST) and alanine transaminase (ALT) increased significantly (P<0.001) due to aspirin supplementation at 4th as well as 6th week of age. While H:L ratio, serum corticosteron and serum cholesterol (only at 42nd day of age) decreased significantly (P<0.001) in aspirin supplemented groups at 28th as well as 42nd day of age. Supplementation of aspirin at 500 mg/kg reduced relative expression of HSP70 in jejunum tissues during 28th or 42nd day of age. It can be concluded that aspirin supplementation 500 mg/kg in diet of heat stressed broilers improved performance as well as welfare.

REFERENCES


  1. Abdel-Fattah, S.A. (2006). Physiological and immunological adjustments of dietary ascorbic acid and acetyl salicylic acid in heat stressed Japanese quail. Egyptian Poultry Science, 26:1395–1418.

  2. Adams, R.L. and Rogler, J.C. (1968). The effects of dietary aspirin and humidity on the performance of light and heavy breed chicks. Poultry Science, 47:1344-1348.

  3. Anwar, B., Khan, S.A., Aslam, A., Maqbool, A. and Khan, K.A. (2004). Effects of ascorbic acid and acetylsalicylic acid supplementation on the performance of broiler chicks exposed to heat stress. Pakistan Veterinary Journal, 24:109-12.

  4. Bustin, S.A., Benes, V., Garson, J.A., Hellemans, J., Huggett, J., Kubista, M., Mueller, R., Nolan, T., Pfaffl, M.W., Shipley, G.L., Vandesompel,e J. and Wittwer, C.T. (2009). The MIQE Guidelines: Minimum Information for Publication of Quantitative Real-Time PCR Experiments. Clinical Chemistry, 55:611–622.

  5. Corrier, D.E. and Deloach, J.R. (1990). Evaluation of cell mediated, cutaneous basophil hypersensitivity in young chickens by an inter digital skin test. Poultry Science, 69: 403-08.

  6. Duncan, D.B. (1955). Multiple ranges and multiple F test. Biometrics, 11:1-42.

  7. Elkholy, M.S. (2008). Some physiological studies on Japanese quail. MSc Thesis, Faculty of Agriculture, Zagazig University, Zagazig, Egypt.

  8. El-Soud, A., Sabriea, B., Ebeid, T.A. and Eid, Y.Z. (2006). Physiological and antioxidative effects of dietary acetyl salicylic acid in laying Japanese quail (coturnix japonica) under high ambient temperature. Journal of Poultry Science, 43:255-265.

  9. Hightwoer, L.E. (1991). Heat shock, stress proteins, chaperones and proteoxicity. Cell, 66:191-7.

  10. Hutchins, M.O., Newcomer, W.S. and Thayer, R.H. (1962). Effect o sodium salicylate on thyroid function in heat-stressed chickens. Poultry Science, 1:1807-1815.

  11. Jordan, F.T.W. (1990). Poultry Diseases, 3 Ed., ELBS, London, pp. 361.

  12. Lecui, Z., Sinhua, L., Shubo,W., Sinzheng, H. and Yongqing, L. (1998). Study on the effect of heat stress onthe morphology of immune organs of broilers. Chinese Journal of Veterinary Medicine, 24: 24-25. 

  13. Lindquist, S. and Craig, E.A. (1988). The heat shock proteins. Annual Review of Genetics, 22:631- 77.

  14. Mohammed, A.A. (2010). Effect of acetyl salicylic acid (ASA) in drinking water on productive performance and blood characteristic of layer hens during heat stress. International Journal of Poultry Science, 9:382-385.

  15. Mujahid, A., Akiba, Y. and Toyomizu, M. (2009). Progressive changes in the physiological responses of heat-stressed broiler chickens. The Journal of Poultry Science, 46:163-167.

  16. Muller, M.J., Acheson, K.J, Jequier, E. and Burger, A.G. (1988). Effect of thyroid hormones on oxidative and nonoxidative glucose metabolism in humans. American Journal of Physiolology Endocrinology and Metabolism, 255:146-    152.

  17. Pfaffl, M.W. (2001). A new mathematical model for relative quantification in real-time RT-PCR. Nucleic Acids Research 29:2002–2007.

  18. Pozniak, B., Hui, Y., Yi , J.N., Guo, C.Z., Deng, S.J., Li, Z., Yin, L., Yang, Y. and Swita³a, M. (2010). Influence of salicylate administration on weight gain and serum biochemical parameters in broiler chickens. Medycyna Weterynaryjna, 66:675-679.

  19. Roussan, D.A., Khwaldeh, G.Y., Haddad, R.R., Shaheen, I.A., Salameh, G. and Al Rifai, R. (2008). Effect of Ascorbic Acid, Acetylsalicylic Acid, Sodium Bicarbonate, and Potassium Chloride Supplementation in Water on the Performance of Broiler Chickens Exposed to Heat Stress. Journal of Applied Poultry Research, 17:141–144.

  20. Sabriea, B., El-Soud, A., Ebeid, T.A. and Eid, Y.Z. (2006). Physiological and anti-oxidative effect of dietary acytyl salicylic acid in laying Japanese quail (Cotrnix japonica) under high ambient temperature. Journal of Poultry Science, 43:255-265.

  21. Sahin, K. and Kucuk, O. (2003). Heat stress and dietary vitamin supplementation of poultry diets. Nutrition Abstracts and Reviews. Series B: Livestock Feeds and Feeding,73:41R–50R.

  22. Sahin, K., Smith, M.O., Onderci, M., Sahin, N., Gursu, M.F. and Kucuk, O. (2005). Supplementation of zinc from organic or inorganic source improves performance and antioxidant status of heat-distressed quail. Poultry Science, 84:882–    887.

  23. Shlosberg, A., Bellaiche, M., Zeitlin, G., Yaacobi, M. and Cahaner, A. (1996). Haematocrit values and mortality from ascites in cold-stressed broiler from parents selected by haematocrit. Poult. Sci., 75: 1-5.

  24. Siegel, H. S. (1995). Stress, strains and resistance. British Poultry Science, 36:3–22.

  25. Siegel, P.B. and Gross, W.B. (1980). Production and persistency of antibodies in chickens to sheep erythrocytes. 1. Directional selection. Poultry Science, 59:1-5.

  26. Snedecor, G.W. and Cochran, W.G. (1989). Statistical Methods. 8th edition Iowa State University Press, Ames, Iowa, Reprinted in 1994. East-West Press Pvt. Ltd., New Delhi.

  27. Star, L., Decuypere, E., Parmentier, H.K. and Kemp, B. (2008). Effect of single or combined climatic and hygienic stress in four layer lines: 2. Endocrine and oxidative stress responses. Poultry sciences, 87:1031-1038.

  28. Tras, B., Inal, F., Bas. A.L., Altunok. V., Elmas, M. and Yazar. E. (2000). Effects of continuous supplementations of ascorbic acid, aspirin, vitamin E and selenium on some hematological parameters and serum superoxide dismutase level in broiler chickens. British Poultry Science, 41:664-666.

  29. Wang, S. and Edens, F.W. (1998). Heat conditioning induces heat shock proteins in broiler chickens and turkey poults. Poultry Science, 77:1636-1645.

  30. Weissmann, G. (1991). Aspirin. American journal of science, 264:84-89.

     
Reviewed By

Download Article
In this Article
    Contact us
    Follow us

    Editorial Board

    View all (0)